[HTML][HTML] State-of-the-art dermatophyte infections: epidemiology aspects, pathophysiology, and resistance mechanisms
The burden of fungal infections is not widely appreciated. Although these infections are
responsible for over one million deaths annually, it is estimated that one billion people are …
responsible for over one million deaths annually, it is estimated that one billion people are …
[HTML][HTML] Epidemiology and diagnostic perspectives of dermatophytoses
MF Petrucelli, MH Abreu, BAM Cantelli, GG Segura… - Journal of Fungi, 2020 - mdpi.com
Dermatophytoses affect about 25% of the world population, and the filamentous fungus
Trichophyton rubrum is the main causative agent of this group of diseases. Dermatomycoses …
Trichophyton rubrum is the main causative agent of this group of diseases. Dermatomycoses …
Keratin hydrolysis by dermatophytes
DK Mercer, CS Stewart - Medical mycology, 2019 - academic.oup.com
Dermatophytes are the most common cause of superficial fungal infections (tinea infections)
and are a specialized group of filamentous fungi capable of infecting and degrading …
and are a specialized group of filamentous fungi capable of infecting and degrading …
[HTML][HTML] Metabolomic analysis of Trichophyton rubrum and Microsporum canis during keratin degradation
A Ciesielska, A Kawa, K Kanarek, A Soboń… - Scientific reports, 2021 - nature.com
Keratin is important and needed for the growth of dermatophytes in the host tissue. In turn,
the ability to invade keratinised tissues is defined as a pivotal virulence attribute of this group …
the ability to invade keratinised tissues is defined as a pivotal virulence attribute of this group …
[HTML][HTML] Transcriptome-wide survey of gene expression changes and alternative splicing in Trichophyton rubrum in response to undecanoic acid
NS Mendes, TA Bitencourt, PR Sanches… - Scientific reports, 2018 - nature.com
While fatty acids are known to be toxic to dermatophytes, key physiological aspects of the
Trichophyton rubrum response to undecanoic acid (UDA), a medium chain saturated fatty …
Trichophyton rubrum response to undecanoic acid (UDA), a medium chain saturated fatty …
[HTML][HTML] Chalcones repressed the AURKA and MDR proteins involved in metastasis and multiple drug resistance in breast cancer cell lines
TT Komoto, TM Bernardes, TB Mesquita, LFB Bortolotto… - Molecules, 2018 - mdpi.com
In the present investigation, trans-chalcone and licochalcone A were tested against MCF-7
and BT-20 breast cancer cell lines for anti-tumor activity. We found that both chalcones down …
and BT-20 breast cancer cell lines for anti-tumor activity. We found that both chalcones down …
[HTML][HTML] Dermatophyte infection: from fungal pathogenicity to host immune responses
R Deng, X Wang, R Li - Frontiers in Immunology, 2023 - frontiersin.org
Dermatophytosis is a common superficial infection caused by dermatophytes, a group of
pathogenic keratinophilic fungi. Apart from invasion against skin barrier, host immune …
pathogenic keratinophilic fungi. Apart from invasion against skin barrier, host immune …
[HTML][HTML] Dual RNA-Seq Analysis of Trichophyton rubrum and HaCat Keratinocyte Co-Culture Highlights Important Genes for Fungal-Host Interaction
MF Petrucelli, K Peronni, PR Sanches, TT Komoto… - Genes, 2018 - mdpi.com
The dermatophyte Trichophyton rubrum is the major fungal pathogen of skin, hair, and nails
that uses keratinized substrates as the primary nutrients during infection. Few strategies are …
that uses keratinized substrates as the primary nutrients during infection. Few strategies are …
Caffeic acid and licochalcone A interfere with the glyoxylate cycle of Trichophyton rubrum
BAM Cantelli, TA Bitencourt, TT Komoto… - Biomedicine & …, 2017 - Elsevier
Trichophyton rubrum is the most common causative agent of dermatomycoses worldwide.
Despite the increasing incidence of fungal infections, the number of commercially available …
Despite the increasing incidence of fungal infections, the number of commercially available …
[HTML][HTML] Exploring the Therapeutic Potential of trans-Chalcone: Modulation of MicroRNAs Linked to Breast Cancer Progression in MCF-7 Cells
TT Komoto, FG Nishimura, AF Evangelista… - International Journal of …, 2023 - mdpi.com
Breast cancer is responsible for 25% of all cancers that affect women. Due to its high
heterogeneity pattern in clinical diagnosis and its molecular profile differences, researchers …
heterogeneity pattern in clinical diagnosis and its molecular profile differences, researchers …