Role of protein arginine methyltransferase 1 in obesity‐related metabolic disorders: Research progress and implications
X Xuan, Y Zhang, Y Song, B Zhang… - Diabetes, Obesity …, 2024 - Wiley Online Library
Obesity has become a major global problem that significantly confers an increased risk of
developing life‐threatening complications, including type 2 diabetes mellitus, fatty liver …
developing life‐threatening complications, including type 2 diabetes mellitus, fatty liver …
[HTML][HTML] Hepatic PRMT1 ameliorates diet-induced hepatic steatosis via induction of PGC1α
L Xu, Z Huang, T Lo, JTH Lee, R Yang, X Yan, D Ye… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Over-nutrition will lead to overexpression of PRMT1 but protein hypomethylation
is observed in the liver of obese subjects. The dynamic alteration of the expression and …
is observed in the liver of obese subjects. The dynamic alteration of the expression and …
[HTML][HTML] Tissue damage, antioxidant capacity, transcriptional and metabolic regulation of red drum Sciaenops ocellatus in response to nanoplastics exposure and …
Z Sun, L Zhao, X Peng, M Yan, S Ding, J Sun… - … and Environmental Safety, 2024 - Elsevier
Nanoplastics are recognized as emerging contaminants that can cause severe toxicity to
marine fishes. However, limited researches were focusing on the toxic effects of …
marine fishes. However, limited researches were focusing on the toxic effects of …
An updated review on the significance of DNA and protein methyltransferases and de-methylases in human diseases: From molecular mechanism to novel therapeutic …
M Ghanbari, NS Khosroshahi, M Alamdar… - Current Medicinal …, 2023 - europepmc.org
Epigenetic mechanisms are crucial in regulating gene expression. These mechanisms
include DNA methylation and histone modifications, like methylation, acetylation, and …
include DNA methylation and histone modifications, like methylation, acetylation, and …
Inhibition of protein arginine methyltransferase 1 alleviates liver fibrosis by attenuating the activation of hepatic stellate cells in mice
FZ Yan, H Qian, F Liu, CH Ding, SQ Liu… - The FASEB …, 2022 - Wiley Online Library
Abstract Protein arginine methyltransferase 1 (PRMT1) has been reported to be involved in
various diseases. The expression of PRMT1 was increased in cirrhotic livers from human …
various diseases. The expression of PRMT1 was increased in cirrhotic livers from human …
[HTML][HTML] MiR-574-3p inhibits glucose toxicity-induced pancreatic β-cell dysfunction by suppressing PRMT1
L Lv, X Wang, J Shen, Y Cao, Q Zhang - Diabetology & Metabolic …, 2022 - Springer
Background Pancreatic β-cell dysfunction is commonly observed in patients with type 2
diabetes mellitus. Protein arginine methyltransferase 1 (PRMT1) plays an important role in …
diabetes mellitus. Protein arginine methyltransferase 1 (PRMT1) plays an important role in …
The Design, Synthesis and in vitro Evaluation of Proteolysis Targeting Chimeras (PROTACs) for the Degradation of Protein Arginine Methyltransferase 1
P Martin - 2024 - repository.cam.ac.uk
Abstract Protein arginine methyltransferase 1 (PRMT1) is a protein responsible for the
asymmetric dimethylation of arginine. PRMT1 is upregulated in a wide range of cancers and …
asymmetric dimethylation of arginine. PRMT1 is upregulated in a wide range of cancers and …
[HTML][HTML] The Role of Protein Arginine Methyltransferase 1 in Gastrointestinal Cancers
J Zou, W Shen, Y Zhang, S Ying - Post-Translational Modifications …, 2021 - intechopen.com
Mammals can produce nine kinds of arginine methylation enzymes that can be divided into
three types (I, II, and III) according to their catalytic activity. Arginine methyltransferase 1 …
three types (I, II, and III) according to their catalytic activity. Arginine methyltransferase 1 …