Tissue‐resident memory T cells and lung immunopathology

IS Cheon, YM Son, J Sun - Immunological Reviews, 2023 - Wiley Online Library
Rapid reaction to microbes invading mucosal tissues is key to protect the host against
disease. Respiratory tissue‐resident memory T (TRM) cells provide superior immunity …

Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2

KL Hilligan, S Namasivayam, CS Clancy… - Nature …, 2023 - nature.com
Abstract Type-1 and type-3 interferons (IFNs) are important for control of viral replication;
however, less is known about the role of Type-2 IFN (IFNγ) in anti-viral immunity. We …

SARS-CoV-2: The Interplay Between Evolution and Host Immunity

JB Case, S Jain, MS Suthar… - Annual Review of …, 2024 - annualreviews.org
The persistence of SARS-CoV-2 infections at a global level reflects the repeated emergence
of variant strains encoding unique constellations of mutations. These variants have been …

Pivotal role of tissue-resident memory lymphocytes in the control of mucosal infections: can mucosal vaccination induce protective tissue-resident memory T and B …

S Longet, S Paul - Frontiers in Immunology, 2023 - frontiersin.org
Tissue-resident memory lymphocytes at mucosal surfaces have been shown to be critical in
long-term protection following mucosal infection. Tissue-resident memory T cells (Trm) have …

Anti-viral activity of bioactive molecules of silymarin against COVID-19 via in silico studies

C Zhang, Y Sui, S Liu, M Yang - Pharmaceuticals, 2023 - mdpi.com
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection drove the
global coronavirus disease 2019 (COVID-19) pandemic, causing a huge loss of human life …

Th2 and Th17‐associated immunopathology following SARS‐CoV‐2 breakthrough infection in Spike‐vaccinated ACE2‐humanized mice

T Zhang, N Magazine, MC McGee… - Journal of Medical …, 2024 - Wiley Online Library
Vaccines have demonstrated remarkable effectiveness in protecting against COVID‐19;
however, concerns regarding vaccine‐associated enhanced respiratory diseases (VAERD) …

Durability of immune responses to SARS-CoV-2 infection and vaccination

MS Suthar - Seminars in Immunology, 2024 - Elsevier
Infection with SARS-CoV-2 in humans has caused a pandemic of unprecedented
dimensions. SARS-CoV-2 is primarily transmitted through respiratory droplets and targets …