[HTML][HTML] Sulforaphane: A broccoli bioactive phytocompound with cancer preventive potential

AE Kaiser, M Baniasadi, D Giansiracusa… - Cancers, 2021 - mdpi.com
There is substantial and promising evidence on the health benefits of consuming broccoli
and other cruciferous vegetables. The most important compound in broccoli, glucoraphanin …

Sulforaphane: A review of its therapeutic potentials, advances in its nanodelivery, recent patents, and clinical trials

B Mangla, S Javed, MH Sultan, P Kumar… - Phytotherapy …, 2021 - Wiley Online Library
Traditionally, herbal supplements have shown an exceptional potential of desirability for the
prevention of diseases and their treatment. Sulforaphane (SFN), an organosulfur compound …

Sulforaphane as an anticancer molecule: Mechanisms of action, synergistic effects, enhancement of drug safety, and delivery systems

MM Kamal, S Akter, CN Lin, S Nazzal - Archives of pharmacal research, 2020 - Springer
Sulforaphane is an isothiocyanate compound that has been derived from cruciferous
vegetables. It was shown in numerous studies to be active against multiple cancer types …

Sulforaphane as a potential remedy against cancer: Comprehensive mechanistic review

S Khan, KA Awan, MJ Iqbal - Journal of Food biochemistry, 2022 - Wiley Online Library
Sulforaphane belongs to the active class of isothiocyanates capable of delivering various
biological benefits for health promotion and disease prevention. This compound is …

Withania somnifera: From prevention to treatment of cancer

DL Palliyaguru, SV Singh… - Molecular nutrition & food …, 2016 - Wiley Online Library
The identification of bioactive molecules that have potential to interrupt carcinogenesis
continues to garner research interest. In particular, molecules that have dietary origin are …

Amygdalin induces apoptosis in human cervical cancer cell line HeLa cells

YU Chen, J Ma, F Wang, J Hu, A Cui… - …, 2013 - Taylor & Francis
Amygdalin, a naturally occurring substance, has been suggested to be efficacious as an
anticancer substance. The effect of amygdalin on cervical cancer cells has never been …

Dietary isothiocyanates inhibit cancer progression by modulation of epigenome

MK Sundaram, R Preetha, S Haque, N Akhter… - Seminars in Cancer …, 2022 - Elsevier
Cell cycle, growth, survival and metabolism are tightly regulated together and failure in
cellular regulation leads to carcinogenesis. Several signaling pathways like the PI3K, WNT …

Extraction, chemical characterization and biological activity determination of broccoli health promoting compounds

AM Ares, MJ Nozal, J Bernal - Journal of Chromatography A, 2013 - Elsevier
Broccoli (Brassica oleracea L. var. Italica) contains substantial amount of health-promoting
compounds such as vitamins, glucosinolates, phenolic compounds, and dietary essential …

Brassica-Derived Plant Bioactives as Modulators of Chemopreventive and Inflammatory Signaling Pathways

C Sturm, AE Wagner - International Journal of Molecular Sciences, 2017 - mdpi.com
A high consumption of vegetables belonging to the Brassicaceae family has been related to
a lower incidence of chronic diseases including different kinds of cancer. These beneficial …

Targeting cellular senescence in cancer by plant secondary metabolites: A systematic review

S Fakhri, SZ Moradi, A Ash-Rafzadeh… - Pharmacological …, 2022 - Elsevier
Senescence suppresses tumor growth, while also developing a tumorigenic state in the
nearby cells that is mediated by senescence-associated secretory phenotypes (SASPs). The …