Intervertebral disc degeneration (IVDD) is a frequent and intractable chronic condition in
orthopedics that causes enormous discomfort in patients' lives and thoughts, as well as a …

Intervertebral disc degeneration (IDD), a progressive and multifactorial pathological process,
is predominantly associated with low back pain and permanent disability. Pyroptosis is a …

Tissue engineering has promising applications in the treatment of intervertebral disc
degeneration (IDD). The annulus fibrosus (AF) is critical for maintaining the physiological …

Background Estimating the contribution of endplate oedema known as Modic changes to
lower back pain (LBP) has been the subject of multiple observational studies and reviews …

Background Intervertebral disc degeneration (IVDD) is a leading cause of low back pain
(LBP). The pathological process of IVDD is associated with inflammatory reactions and …

Intervertebral disc degeneration (IVDD) is one of the leading causes of lower back pain.
Although IVDD cannot directly cause death, it can cause pain, psychological burdens, and …

Substantial evidence supports that chronic low back pain is associated with intervertebral
disc degeneration (IDD), which is accompanied by decreased cell activity and matrix …

Low back pain is a very common symptom in people all over the world, which is now the
leading cause of disability worldwide 1, 2. Although the specific cause of low back pain is …

Background Vertebral endplate sclerosis and facet osteoarthritis have been documented in
animals and humans. However, it is unclear how these adjacent pathologies engage in …

Objective Investigate associations between endplate and motion segment magnetic
resonance imaging (MRI) characteristics and treatment outcomes following basivertebral …