Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

l‐Cysteine is a nutritionally semiessential amino acid and is present mainly in the form of l‐
cystine in the extracellular space. With the help of a transport system, extracellular l‐cystine …

NADPH oxidase as an important source of intracellular reactive oxygen species (ROS) has
gained enormous importance over the years, and the detailed structures of all the …

Alzheimer's disease (AD) is a neurodegenerative disorder representing the major cause of
dementia. It is characterized by memory loss, and cognitive and behavioral decline. In …

Lipoic acid (LA) is an antioxidant able to produce its effects in aqueous or lipophilic
environments. Lipoate is the conjugate base of lipoic acid, and the most prevalent form of LA …

The incidence of neurodegenerative diseases has increased greatly worldwide due to the
rise in life expectancy. In spite of notable development in the understanding of these …

Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the
formation of intracellular neurofibrillary tangles (NFTs) and extracellular amyloid plaques …

Oxidative stress and inflammatory response are important elements of Alzheimer's disease
(AD) pathogenesis, but the role of redox signaling cascade and its cross-talk with …

The aging of brain in the absence of neurodegenerative diseases, usually called non-
pathological brain aging or normal cognitive aging, is characterized by an impairment of …

Taking into account that pro-inflammatory cytokines and oxidative and nitrosative stress are
implicated in the pathogenesis of depression and that α-tocopherol has antidepressant, anti …