Matrix metalloproteinases (MMPs) are a group of endopeptidases that play a vital role in the
restoration of damaged skin. Through mediating various cellular events such as …

The proteolytic processing of collagen (collagenolysis) is critical in development and
homeostasis, but also contributes to numerous pathologies. Mammalian interstitial …

Enzymatic proteolysis of cell surface proteins and extracellular matrix (ECM) is critical for
tissue homeostasis and cell signaling. These proteolytic activities are mediated …

1. Diabetic chronic wounds, mainly foot ulcers, constitute one of the most common
complications of poorly managed diabetes mellitus. The most typical reasons are insufficient …

Cutaneous wound healing is a complex mechanism with multiple processes orchestrating
harmoniously for structural and functional restoration of the damaged tissue. Chronic non …

All vertebrates possess mechanisms to restore damaged tissues with outcomes ranging
from regeneration to scarring. Unfortunately, the mammalian response to tissue injury most …

The extracellular matrix (ECM) is a complex and dynamic structure made up of an estimated
300 different proteins. The ECM is also a rich source of cytokines and growth factors in …

The periodontal ligament (PDL) plays a critical role in providing immediate response to
abrupt high loads during mastication while also facilitating slow remodeling of the alveolar …

The extracellular matrix (ECM), composed of interlinked proteins outside of cells, is an
important component of the human body that helps maintain tissue architecture and cellular …

Three-dimensional (3D) printing, also known as additive manufacturing, was first introduced
in 1986. 1 Unlike the techniques that can only be used for mass-produced goods in classical …