A synthesis of 4-amino-5-(2-thienyl)-1, 2, 4-triazol (4 H)-3-ylthioacetanilides was developed,
and these were chemically modified to produce 2-[5-(2′-thienyl-4-(1 H-1-pyrrolyl)-4 H-1, 2 …

Pathogenic infections and inflammation are very common ailments humans suffer. Upsurge
of resistant pathogens has impeded the antimicrobial drug development process in recent …

In the present work, 25 of novel 1, 2, 4-triazole (4H) derivatives were evaluated for their anti-
tumor activity through docking studies and antitumor screening in vitro. The target protein …

With the purpose of searching the objective parameters of dependence of the activity of
Bupleurum aureum plant on the components of its chemical composition and determining …

Apigenin is best known as an irreversible inhibitor of monoamine oxidase (MAO), an
intracellular enzyme associated with the outer membrane of mitochondria. The purpose of …

In this work, the series of new 4-phenyl-5-4-(R)-phenoxymethyl-1, 2, 4-triazole-3-ylthio-1-
(R1)-acetophenones have been synthesized by alkylation of correspondent 4-phenyl-5 …

The 1, 2, 4-triazole ring is an important heterocyclic ring having various synthetic uses.
Triazole derivatives have been synthesized and published by various researchers as its …

Aim. A targeted synthesis of the potential anti-inflammatory agents–4-amino-5-(pyridin-2-yl)-
and 4-amino-5-(pyridin-3-yl)-1, 2, 4-triazole (4H)-3-ylthio acetamides. Materials and …

Аннотация Разработан синтез 4-амино-5-(2-тиенил)-1, 2, 4-триазол (4H)-3-
илтиоацетанилидов, осуществлена их химическая модификация в 2-[5-(2'-тиенил-4-(1H …

Для целенаправленного синтеза новых биологически активных веществ в ряду
производных 1, 2, 4-триазола разработана препаративная методика синтеза и …