[HTML][HTML] GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential
Type 2 diabetes mellitus (T2DM) is closely associated with cardiovascular diseases (CVD),
including atherosclerosis, hypertension and heart failure. Some anti-diabetic medications …
including atherosclerosis, hypertension and heart failure. Some anti-diabetic medications …
Roles of reactive oxygen species in biological behaviors of prostate cancer
C Han, Z Wang, Y Xu, S Chen, Y Han… - BioMed research …, 2020 - Wiley Online Library
Prostate cancer (PCa), known as a heterogenous disease, has a high incidence and
mortality rate around the world and seriously threatens public health. As an inevitable by …
mortality rate around the world and seriously threatens public health. As an inevitable by …
Oxidative stress and redox-dependent signaling in prostate cancer
EV Kalinina, LA Gavriliuk, VS Pokrovsky - Biochemistry (Moscow), 2022 - Springer
Tumor emergence and progression is complicated by the dual role of reactive oxygen
species (ROS). Low concentrations of ROS are essential for many intracellular metabolic …
species (ROS). Low concentrations of ROS are essential for many intracellular metabolic …
[HTML][HTML] Glucose control independent mechanisms involved in the cardiovascular benefits of glucagon-like peptide-1 receptor agonists
Q Wu, D Li, C Huang, G Zhang, Z Wang, J Liu… - Biomedicine & …, 2022 - Elsevier
Patients with type 2 diabetes mellitus (T2DM) face a high risk of developing cardiovascular
diseases. However, traditional hypoglycemic drugs have limited effects on macrovascular …
diseases. However, traditional hypoglycemic drugs have limited effects on macrovascular …
Fenugreek seed galactomannan aqueous and extract protects against diabetic nephropathy and liver damage by targeting NF-κB and Keap1/Nrf2 Axis
SM Alsuliam, NA Albadr, SA Almaiman, AS Al-Khalifah… - Toxics, 2022 - mdpi.com
This investigation was conducted to test the potential of the galactomannan (F-GAL) and
aqueous extract (FS-AE) of the Fenugreek seed aqueous to prevent liver and kidney …
aqueous extract (FS-AE) of the Fenugreek seed aqueous to prevent liver and kidney …
Exendin-4 attenuates remodeling in the remote myocardium of rats after an acute myocardial infarction by activating β-arrestin-2, protein phosphatase 2A, and …
RA Eid, MA Khalil, MA Alkhateeb, SM Eleawa… - … drugs and therapy, 2021 - Springer
Purpose This study tested if the protective anti-remodeling effect of GLP-1 agonist Exendin-4
after an acute myocardial infarction (MI) in rats involves inhibition of the Wnt1/β-catenin …
after an acute myocardial infarction (MI) in rats involves inhibition of the Wnt1/β-catenin …
[HTML][HTML] circRNA-miRNA complex participates in the apoptosis of myocardial cells in myocardial ischemia/reperfusion injury
Y Sun, Y Zhang, Z Ye, Y Wang, Y Lao… - Discovery …, 2022 - discoverymedicine.com
Myocardial ischemia/reperfusion (I/R) injury is a common condition. This study aimed to
investigate the potential mechanisms of circ_Ddx60 in the mouse model of I/R injury …
investigate the potential mechanisms of circ_Ddx60 in the mouse model of I/R injury …
Pathophysiology and Advances in the Therapy of Cardiomyopathy in Patients with Diabetes Mellitus
P Graczyk, A Dach, K Dyrka, A Pawlik - International Journal of Molecular …, 2024 - mdpi.com
Diabetes mellitus (DM) is known as the first non-communicable global epidemic. It is
estimated that 537 million people have DM, but the condition has been properly diagnosed …
estimated that 537 million people have DM, but the condition has been properly diagnosed …
[PDF][PDF] Exendin-4 differentially modulates essential functions of human dermal fibroblasts under normoglycemic and hyperglycemic conditions.
M Wolak, J Drobnik, E Bojanowska - Journal of Physiology & …, 2021 - jpp.krakow.pl
Evidence that exendin-4, a glucagon-like peptide-1 analog, might be used to treat poorly
healing wounds under diabetic and nondiabetic conditions has gained increasing interest …
healing wounds under diabetic and nondiabetic conditions has gained increasing interest …
胰高血糖素样肽1 受体激动剂对高糖高脂环境下大鼠心肌细胞损伤的改善作用及其铁死亡机制
孟根托娅 - 吉林大学学报(医学版), 2023 - xuebao.jlu.edu.cn
目的目的: 探讨胰高血糖素样肽1 受体(GLP-1R) 激动剂Exendin-4 (E4) 对高糖高脂(HGHL)
环境下心肌细胞损伤的影响, 阐明其相关机制. 方法: 大鼠心肌H9C2 细胞分为对照组, HGHL 组 …
环境下心肌细胞损伤的影响, 阐明其相关机制. 方法: 大鼠心肌H9C2 细胞分为对照组, HGHL 组 …