Overweight and obesity in pregnancy: their impact on epigenetics

C Reichetzeder - European journal of clinical nutrition, 2021 - nature.com
Over the last few decades, the prevalence of obesity has risen to epidemic proportions
worldwide. Consequently, the number of obesity in pregnancy has risen drastically …

A comprehensive approach to modeling maternal immune activation in rodents

MC Bucknor, A Gururajan, RC Dale… - Frontiers in …, 2022 - frontiersin.org
Prenatal brain development is a highly orchestrated process, making it a very vulnerable
window to perturbations. Maternal stress and subsequent inflammation during pregnancy …

Programming effects of maternal and gestational obesity on offspring metabolism and metabolic inflammation

E Chang, H Hafner, M Varghese, C Griffin… - Scientific Reports, 2019 - nature.com
With the increasing prevalence of obesity in women of reproductive age there is a need to
understand the ramifications of this on offspring. The purpose of this study is to investigate …

Review shows that maternal obesity induces serious adverse neonatal effects and is associated with childhood obesity in their offspring

D Mitanchez, P Chavatte‐Palmer - Acta paediatrica, 2018 - Wiley Online Library
Aim Obesity at the start of pregnancy has been rising worldwide, increasing the risk of
maternal complications. We reviewed the independent effects of maternal obesity during …

Early-life nutrition and metabolic disorders in later life: A new perspective on energy metabolism

LY Zhou, MQ Deng, Q Zhang, XH Xiao - Chinese medical journal, 2020 - mednexus.org
Type 2 diabetes mellitus and metabolic disorders have become an epidemic globally.
However, the pathogenesis remains largely unclear and the prevention and treatment are …

[HTML][HTML] In utero programming and early detection of cardiovascular disease in the offspring of mothers with obesity

K Van De Maele, R Devlieger, I Gies - Atherosclerosis, 2018 - Elsevier
The offspring of women with obesity during their pregnancy are exposed to an altered intra-
uterine environment. A subsequent influence on the cardiovascular development during …

Maternal genistein intake mitigates the deleterious effects of high-fat diet on glucose and lipid metabolism and modulates gut microbiota in adult life of male mice

L Zhou, X Xiao, Q Zhang, J Zheng, M Deng - Frontiers in Physiology, 2019 - frontiersin.org
Adverse early-life exposures program increased risk of chronic metabolic diseases in
adulthood. However, the effects of genistein supplementation in early life on metabolic …

[PDF][PDF] Obesity in pregnancy: a novel concept on the roles of adipokines in uterine contractility

J Hajagos-Tóth, E Ducza, R Samavati, SG Vari… - Croatian Medical …, 2017 - hrcak.srce.hr
Obesity is a global health problem among pregnant women and an increasing problem in
medical practice (1, 2). The most negative consequence of obesity is the development of …

Different statistical approaches to characterization of adipocyte size in offspring of obese rats: effects of maternal or offspring exercise intervention

CA Ibáñez, M Vázquez-Martínez… - Frontiers in …, 2018 - frontiersin.org
Adipocyte size (AS) shows asymmetric distribution related to current metabolic state, eg,
adipogenesis or lipolysis. We profiled AS distribution using different statistical approaches in …

Effects of maternal resveratrol on maternal high-fat diet/obesity with or without postnatal high-fat diet

MH Hsu, JM Sheen, IC Lin, HR Yu, MM Tiao… - International Journal of …, 2020 - mdpi.com
To examine the effects of maternal resveratrol in rats borne to dams with gestational high-fat
diet (HFD)/obesity with or without postnatal high-fat diet. We first tested the effects of …