T cell cytoarchitecture differs dramatically depending on whether the cell is circulating within
the bloodstream, migrating through tissues, or interacting with antigen-presenting cells. The …

The complement system is an ancient and evolutionarily conserved effector system
comprising in mammals over 50 circulating and membrane bound proteins. Complement …

Endocytosis supports cell communication, growth, and pathogen infection. The species B
human adenovirus serotype 3 (Ad3) is associated with epidemic conjunctivitis, and fatal …

Complement is undeniably quintessential for innate immunity by detecting and eliminating
infectious microorganisms. Recent work, however, highlights an equally profound impact of …

ABSTRACT Human adenovirus serotype 35 (HAdV-35; here referred to as Ad35) causes
kidney and urinary tract infections and infects respiratory organs of immunocompromised …

Laboratory adapted and vaccine strains of measles virus (MV) induced type I IFN in infected
cells. The wild-type strains in contrast induced it to a far lesser extent. We have investigated …

CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is
expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic …

The aberrant expression of human endogenous retrovirus (HERV) elements of the HERV-W
family has been associated with different diseases, including multiple sclerosis (MS). In …

Complement is a system of blood plasma proteins that play critical roles in host defense
through attracting leukocytes to sites of inflammation, mediating myeloid cell uptake and …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS). In the recent years, accumulating evidence has supported an …