Abstract The oncofetal protein, 5T4, is a tumor-associated protein displayed on the cell
membrane of various carcinomas. This molecule is a promising target for anti-tumor vaccine …

Nasopharyngeal carcinoma (NPC) is a major cause of cancer-related death in Southeast
Asia and China. Metastasis and relapse are the primary cause of morbidity and mortality in …

Purpose The cell adhesion molecule integrin α v β 3 is an important player in the process of
tumor angiogenesis and metastasis. Abegrin™, a fully humanized anti-integrin α v β 3 …

Purpose Preclinical in vivo analyses of treatment responses are an important prerequisite to
evaluate new therapeutics. Molecular in vivo imaging in the far red (FR)/near infra red (NIR) …

Anal cancer patients who have exhibited disease progression after having received all
approved drugs pose a major therapeutic challenge. In addition to cytotoxic agents, novel …

Radioimmunotherapy (RIT) is a promising approach for the treatment of a wide variety of
malignancies. The aim of this study was to investigate the therapeutic efficacy of 131I …

To improve efficacy and minimize toxicity of EGFR inhibition treatment, we developed
Ame55, a novel anti‐EGFR IgG1 with lower affinity to EGFR than cetuximab (C225) from a …

Purpose: Internalization is one of the key steps for anticancer immunoconjugates to deliver
the drugs inside of cancer cells. Herein, the internalization property of antiepidermal growth …

Provided are fusion proteins between p97 (melanotransferrin) and iduronate-2-sulfatase
(IDS), and related compositions and methods of use thereof, for instance, to facilitate …

US9993530B2 - Fragments of P97 and uses thereof - Google Patents US9993530B2 - Fragments
of P97 and uses thereof - Google Patents Fragments of P97 and uses thereof Download PDF Info …