Targeting dorsal root ganglia for chemotherapy-induced peripheral neuropathy: from bench to bedside
Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating condition affecting an
increasing number of cancer survivors worldwide. However, insights into its pathophysiology …
increasing number of cancer survivors worldwide. However, insights into its pathophysiology …
[HTML][HTML] Nucleoside Reverse Transcriptase Inhibitor (NRTI)-Induced Neuropathy and Mitochondrial Toxicity: Limitations of the Poly-γ Hypothesis and the Potential …
Nucleoside reverse transcriptase inhibitors (NRTIs) are the backbone of highly active
antiretroviral therapy (HAART)—the current standard of care for treating human …
antiretroviral therapy (HAART)—the current standard of care for treating human …
Duloxetine prevents bortezomib and paclitaxel large-fiber chemotherapy-induced peripheral neuropathy (LF-CIPN) in sprague dawley rats
N Mansooralavi, EV Khomula, JD Levine - Molecular Pain, 2023 - journals.sagepub.com
Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating, treatment-limiting,
side-effect of several classes of chemotherapy drugs. While negatively impacting oncology …
side-effect of several classes of chemotherapy drugs. While negatively impacting oncology …
Vascular dysfunction is at the onset of oxaliplatin-induced peripheral neuropathy symptoms in mice
Oxaliplatin-induced peripheral neuropathy (OIPN) is an adverse side effect of this
chemotherapy used for gastrointestinal cancers. The continuous pain experienced by OIPN …
chemotherapy used for gastrointestinal cancers. The continuous pain experienced by OIPN …
Proton Pump Inhibitors Ameliorate Oxaliplatin-induced Peripheral Neuropathy: Retrospective Analysis of Two Real-world Clinical Databases
A Kobayashi, K Ikemura, E Wakai, M Kondo… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Chemotherapy-induced peripheral neuropathy (CIPN) due to oxaliplatin (L-
OHP) is a major clinical problem. Effective and safe preventive strategies for CIPN are …
OHP) is a major clinical problem. Effective and safe preventive strategies for CIPN are …
DRG explant model: elucidating mechanisms of oxaliplatin-induced peripheral neuropathy and identifying potential therapeutic targets
J Du, LC Sudlow, ID Luzhansky, MY Berezin - bioRxiv, 2023 - biorxiv.org
Oxaliplatin triggered chemotherapy induced peripheral neuropathy (CIPN) is a common and
debilitating side effect of cancer treatment which limits the efficacy of chemotherapy and …
debilitating side effect of cancer treatment which limits the efficacy of chemotherapy and …