The oral microbiome in the pathophysiology of cardiovascular disease

A Tonelli, EN Lumngwena, NAB Ntusi - Nature Reviews Cardiology, 2023 - nature.com
Despite advances in our understanding of the pathophysiology of many cardiovascular
diseases (CVDs) and expansion of available therapies, the global burden of CVD …

[HTML][HTML] Association between periodontal disease and atherosclerotic cardiovascular diseases: revisited

F Zardawi, S Gul, A Abdulkareem, A Sha… - Frontiers in …, 2021 - frontiersin.org
Atherosclerotic cardiovascular disease (ACVD) is an inflammatory disease of the coronary
arteries associated with atheroma formation, which can cause disability and often death …

[HTML][HTML] Porphyromonas gingivalis and Its Systemic Impact: Current Status

F Mei, M Xie, X Huang, Y Long, X Lu, X Wang, L Chen - Pathogens, 2020 - mdpi.com
The relationship between periodontitis and systemic diseases, notably including
atherosclerosis and diabetes, has been studied for several years. Porphyromonas …

Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association? A scientific statement from the American Heart …

PB Lockhart, AF Bolger, PN Papapanou… - Circulation, 2012 - Am Heart Assoc
A link between oral health and cardiovascular disease has been proposed for more than a
century. Recently, concern about possible links between periodontal disease (PD) and …

Periodontal bacterial invasion and infection: contribution to atherosclerotic pathology

L Reyes, D Herrera, E Kozarov… - Journal of clinical …, 2013 - Wiley Online Library
Objective The objective of this review was to perform a systematic evaluation of the literature
reporting current scientific evidence for periodontal bacteria as contributors to …

Gum Bug, Leave My Heart Alone!”—Epidemiologic and Mechanistic Evidence Linking Periodontal Infections and Atherosclerosis

M Kebschull, RT Demmer… - Journal of dental …, 2010 - journals.sagepub.com
Evidence from epidemiologic studies suggests that periodontal infections are independently
associated with subclinical and clinical atherosclerotic vascular disease. Although the …

Periodontal disease and systemic illness: will the evidence ever be enough?

MP Cullinan, GJ Seymour - Periodontology 2000, 2013 - Wiley Online Library
The concept of focal infection or systemic disease arising from infection of the teeth was
generally accepted until the mid‐20th century when it was dismissed because of lack of …

Links between atherosclerotic and periodontal disease

DA Chistiakov, AN Orekhov, YV Bobryshev - Experimental and molecular …, 2016 - Elsevier
Periodontal disease (PD) and cardiovascular disease (CVD) are highly prevalent in the
modern community. Both pathologies are chronic inflammatory disorders, which are …

Mechanisms involved in the association between peridontal diseases and cardiovascular disease

R Teles, CY Wang - Oral diseases, 2011 - Wiley Online Library
Oral Diseases (2011) 17, 450–461 It is now well accepted that besides the cholesterol
associated mechanisms of atherogenesis, inflammation plays a crucial role in all stages of …

Beyond hemostasis: the role of platelets in inflammation, malignancy and infection

A McNicol, SJ Israels - Cardiovascular & Haematological …, 2008 - ingentaconnect.com
Platelets play a complex role in hemostasis and thrombosis. The expression of multiple
membrane receptors, both constitutive and activation-dependent, mediates platelet …