Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice
SY Jiao, YH Yang, SR Chen - Human reproduction update, 2021 - academic.oup.com
BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …
Genetics of primary ovarian insufficiency: new developments and opportunities
Y Qin, X Jiao, JL Simpson… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Primary ovarian insufficiency (POI) is characterized by marked
heterogeneity, but with a significant genetic contribution. Identifying exact causative genes …
heterogeneity, but with a significant genetic contribution. Identifying exact causative genes …
Genetic insights into biological mechanisms governing human ovarian ageing
Reproductive longevity is essential for fertility and influences healthy ageing in women,, but
insights into its underlying biological mechanisms and treatments to preserve it are limited …
insights into its underlying biological mechanisms and treatments to preserve it are limited …
Molecular genetics of premature ovarian insufficiency
X Jiao, H Ke, Y Qin, ZJ Chen - Trends in Endocrinology & Metabolism, 2018 - cell.com
Premature ovarian insufficiency (POI) is highly heterogeneous in genetic etiology. Yet
identifying causative genes has been challenging with candidate gene approaches. Recent …
identifying causative genes has been challenging with candidate gene approaches. Recent …
Genetics of human female infertility
SA Yatsenko, A Rajkovic - Biology of reproduction, 2019 - academic.oup.com
About 10% of women of reproductive age are unable to conceive or carry a pregnancy to
term. Female factors alone account for at least 35% of all infertility cases and comprise a …
term. Female factors alone account for at least 35% of all infertility cases and comprise a …
Genetics of azoospermia
F Cioppi, V Rosta, C Krausz - International Journal of Molecular Sciences, 2021 - mdpi.com
Azoospermia affects 1% of men, and it can be due to:(i) hypothalamic-pituitary
dysfunction,(ii) primary quantitative spermatogenic disturbances,(iii) urogenital duct …
dysfunction,(ii) primary quantitative spermatogenic disturbances,(iii) urogenital duct …
Premature ovarian insufficiency: new perspectives on genetic cause and phenotypic spectrum
Premature ovarian insufficiency (POI) is one form of female infertility, defined by loss of
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …
ovarian activity before the age of 40 and characterized by amenorrhea (primary or …
[HTML][HTML] Premature Ovarian Insufficiency-an update on recent advances in understanding and management
S Torrealday, P Kodaman, L Pal - F1000Research, 2017 - ncbi.nlm.nih.gov
Premature ovarian insufficiency is a complex and relatively poorly understood entity with a
myriad of etiologies and multisystem sequelae that stem from premature deprivation of …
myriad of etiologies and multisystem sequelae that stem from premature deprivation of …
Genetics of ovarian insufficiency and defects of folliculogenesis
MM França, BB Mendonca - … practice & research Clinical endocrinology & …, 2022 - Elsevier
Primary ovarian insufficiency (POI) is determined by exhaustion of follicles in the ovaries,
which leads to infertility before the age of 40 years. It is characterized by a strong familial …
which leads to infertility before the age of 40 years. It is characterized by a strong familial …
Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging
A Capalbo, ER Hoffmann, D Cimadomo… - Human reproduction …, 2017 - academic.oup.com
ABSTRACT BACKGROUND The unbalanced transmission of chromosomes in human
gametes and early preimplantation embryos causes aneuploidy, which is a major cause of …
gametes and early preimplantation embryos causes aneuploidy, which is a major cause of …