Cancer molecular markers: A guide to cancer detection and management

M Nair, SS Sandhu, AK Sharma - Seminars in cancer biology, 2018 - Elsevier
Cancer is generally caused by the molecular alterations which lead to specific mutations.
Advances in molecular biology have provided an impetus to the study of cancers with …

Approach to the thyroid cancer patient with bone metastases

JA Wexler - The Journal of Clinical Endocrinology & Metabolism, 2011 - academic.oup.com
Thyroid cancer incidence has been increasing for de-cades in the United States (1, 2). There
are known risk factors for thyroid cancer including female gender, advancing age, family …

Naringin inhibits thyroid cancer cell proliferation and induces cell apoptosis through repressing PI3K/AKT pathway

J Zhou, L Xia, Y Zhang - Pathology-Research and Practice, 2019 - Elsevier
The present study aimed to investigate the anti-tumor effects of naringin in thyroid cancer
(TC), and to explore the underlying mechanisms. TC cell lines TPC-1 and SW1736 were …

Influence of cigarette smoking on thyroid gland—an update

N Sawicka-Gutaj, P Gutaj, J Sowiński… - Endokrynologia …, 2014 - journals.viamedica.pl
Many studies have shown that cigarette smoking exerts multiple effects on the thyroid gland.
Smoking seems to induce changes in thyroid function tests, like decrease in TSH and …

Circulating cell-free DNA, SLC5A8 and SLC26A4 hypermethylation, BRAFV600E: A non-invasive tool panel for early detection of thyroid cancer

M Zane, M Agostini, MV Enzo, EC Ide… - Biomedicine & …, 2013 - Elsevier
Purpose In the latest years, high levels of circulating cell-free DNA (cf-DNA) have been
found to be associated with cancer diagnosis and progression, and cf-DNA has become a …

The role of miRNA in papillary thyroid cancer in the context of miRNA Let-7 family

E Perdas, R Stawski, D Nowak… - International journal of …, 2016 - mdpi.com
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy. RET/PTC
rearrangement is the most common genetic modification identified in this category of cancer …

Omics sciences and precision medicine in thyroid cancer

K Dhuli, MC Medori, K Donato, PE Maltese… - La Clinica …, 2023 - ricerca.unich.it
Background: Thyroid cancer, a heterogeneous disease originating from the thyroid gland,
stands as the predominant endocrine malignan-cy worldwide. Despite advances in …

[HTML][HTML] Matrine inhibits TPC‑1 human thyroid cancer cells via the miR‑21/PTEN/Akt pathway

L Zhao, X Zhang, S Cui - Oncology Letters, 2018 - spandidos-publications.com
Papillary thyroid cancer (PTC) is the primary type of thyroid cancer and the most widespread
endocrine malignancy. Matrine is a traditional Chinese medicine and has been …

Detection of PAX8/PPARG and RET/PTC Rearrangements Is Feasible in Routine Air-Dried Fine Needle Aspiration Smears

C Ferraz, C Rehfeld, A Krogdahl, EM Precht Jensen… - Thyroid, 2012 - liebertpub.com
Background: The diagnostic limitations of fine needle aspiration (FNA), like the
indeterminate category, can be partially overcome by molecular analysis. As PAX8/PPARG …

Sorafenib for the treatment of thyroid cancer: an updated review

J Krajewska, D Handkiewicz-Junak… - Expert Opinion on …, 2015 - Taylor & Francis
Introduction: Sorafenib (Nexavar) is an oral multi-kinase inhibitor targeting B-type Raf kinase
(BRAF)(both wild type and BRAFV600E), VEGFR1, VEGFR2, VEGFR3, PDGFRβ and RET …