Diseases are frequently caused by disorders of basic cell biological mechanisms that
govern the functions of individual tissues and organs [1]. Detailed knowledge of the …

Robbins Basic Pathology delivers the pathology knowledge you need, the way you need it,
from the name you can trust! This medical textbook's unbeatable author team helps you …

This paper reviews current concepts of glomerular immune injury of both inflammatory and
noninflammatory types. In noninflammatory lesions induced by antibody alone or C5b-9, the …

GLOMERULONEPHRITIS is an inflammation of the kidney characterized by the
accumulation of extracellular matrix within the damaged glomeruli1–4, impaired filtration …

The nephritogenic antigen of Heymann's nephritis (HN), gp330, was previously
demonstrated (4-9) to be a resident glycoprotein of coated pits in the glomerular and …

Lupus autoantibodies interact directly with distinct glomerular and vascular cell surface
antigens. We have identified monoclonal anti-DNA antibodies derived from lupus prone …

Background and objectives: In idiopathic membranous nephropathy (IMN), CD 20 B-cell
depletion by rituximab may induce nephrotic syndrome (NS) remission. Whether this is …

Inhibition of the CD40-CD40ligand pathway prevents murine membranous
glomerulonephritis. Several forms of glomerulonephritis are induced by antibodies against …

Membranous glomerulonephritis (MGN) is a frequent autoimmune disease which accounts
in a large percentage of patients for chronic renal failure (Cameron 1972; Couser 1985a) …

In a time-study of active Heymann nephritis, the expression of agrin, the main heparan
sulfate proteoglycan in the glomerular basement membrane, was analyzed in relation to …