Ion channels and their functional role in vascular endothelium
B Nilius, GUY Droogmans - Physiological reviews, 2001 - journals.physiology.org
Endothelial cells (EC) form a unique signal-transducing surface in the vascular system. The
abundance of ion channels in the plasma membrane of these nonexcitable cells has raised …
abundance of ion channels in the plasma membrane of these nonexcitable cells has raised …
The endothelium, Part I: Multiple functions of the endothelial cells--focus on endothelium-derived vasoactive mediators
M Félétou - 2011 - books.google.com
The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …
Endothelium-dependent hyperpolarization: beyond nitric oxide and cyclic GMP
RA Cohen, PM Vanhoutte - Circulation, 1995 - Am Heart Assoc
Blood flow and blood pressure are determined by an integration of reflex, humoral, and local
vascular control mechanisms. Knowledge of these mechanisms has mushroomed over the …
vascular control mechanisms. Knowledge of these mechanisms has mushroomed over the …
Calcium‐activated potassium channels and endothelial dysfunction: therapeutic options?
M Félétou - British journal of pharmacology, 2009 - Wiley Online Library
The three subtypes of calcium‐activated potassium channels (KCa) of large, intermediate
and small conductance (BKCa, IKCa and SKCa) are present in the vascular wall. In healthy …
and small conductance (BKCa, IKCa and SKCa) are present in the vascular wall. In healthy …
Fluid shear stress induces endothelial transforming growth factor beta-1 transcription and production. Modulation by potassium channel blockade.
M Ohno, JP Cooke, VJ Dzau… - The Journal of clinical …, 1995 - Am Soc Clin Investig
The endothelium has the capacity to modulate vascular structure in response to
hemodynamic stimuli. We tested the hypothesis that exposure of the endothelium to …
hemodynamic stimuli. We tested the hypothesis that exposure of the endothelium to …
Endothelium‐dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis?
TM Griffith - British journal of pharmacology, 2004 - Wiley Online Library
An endothelium‐derived hyperpolarizing factor (EDHF) that is distinct from nitric oxide (NO)
and prostanoids has been widely hypothesized to hyperpolarize and relax vascular smooth …
and prostanoids has been widely hypothesized to hyperpolarize and relax vascular smooth …
Ion channels in vascular endothelium
▪ Abstract The functional impact of ion channels in vascular endothelial cells (ECs) is still a
matter of controversy. This review describes different types of ion channels in ECs and their …
matter of controversy. This review describes different types of ion channels in ECs and their …
Connexins and gap junctions in the EDHF phenomenon and conducted vasomotor responses
C De Wit, TM Griffith - Pflügers Archiv-European Journal of Physiology, 2010 - Springer
It is becoming increasingly evident that electrical signaling via gap junctions plays a central
role in the physiological control of vascular tone via two related mechanisms (1) the …
role in the physiological control of vascular tone via two related mechanisms (1) the …
Inwardly rectifying K+ channels are major contributors to flow‐induced vasodilatation in resistance arteries
SJ Ahn, IS Fancher, JT Bian, CX Zhang… - The Journal of …, 2017 - Wiley Online Library
Key points Endothelial inwardly rectifying K+ (Kir2. 1) channels regulate flow‐induced
vasodilatation via nitric oxide (NO) in mouse mesenteric resistance arteries. Deficiency of …
vasodilatation via nitric oxide (NO) in mouse mesenteric resistance arteries. Deficiency of …
Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium
JM Doughty, F Plane… - American Journal of …, 1999 - journals.physiology.org
In rat mesenteric artery, endothelium-derived hyperpolarizing factor (EDHF) is blocked by a
combination of apamin and charybdotoxin (ChTX). The site of action of these toxins has not …
combination of apamin and charybdotoxin (ChTX). The site of action of these toxins has not …