Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions
Z Megyesfalvi, CM Gay, H Popper… - CA: a cancer journal …, 2023 - Wiley Online Library
Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity.
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
Immunotherapy in lung cancer: current landscape and future directions
H Mamdani, S Matosevic, AB Khalid, G Durm… - Frontiers in …, 2022 - frontiersin.org
Over the past decade, lung cancer treatment has undergone a major paradigm shift. A
greater understanding of lung cancer biology has led to the development of many effective …
greater understanding of lung cancer biology has led to the development of many effective …
A neutrophil response linked to tumor control in immunotherapy
Neutrophils accumulate in solid tumors, and their abundance correlates with poor prognosis.
Neutrophils are not homogeneous, however, and could play different roles in cancer …
Neutrophils are not homogeneous, however, and could play different roles in cancer …
Current treatments for non-small cell lung cancer
Q Guo, L Liu, Z Chen, Y Fan, Y Zhou, Z Yuan… - Frontiers in …, 2022 - frontiersin.org
Despite improved methods of diagnosis and the development of different treatments,
mortality from lung cancer remains surprisingly high. Non-small cell lung cancer (NSCLC) …
mortality from lung cancer remains surprisingly high. Non-small cell lung cancer (NSCLC) …
Evolving role of immunotherapy in small cell lung cancer
ED Barrows, MJ Blackburn, SV Liu - Seminars in Cancer Biology, 2022 - Elsevier
Small cell lung cancer (SCLC) is a highly lethal subtype of lung cancer with a particularly
poor prognosis. For decades, the best available systemic therapy was platinum plus …
poor prognosis. For decades, the best available systemic therapy was platinum plus …
SCLC treatment in the immuno-oncology era: current evidence and unmet needs
L Belluomini, L Calvetti, A Inno, G Pasello… - Frontiers in …, 2022 - frontiersin.org
Small cell lung cancer (SCLC) represents about 13%–15% of all lung cancers. It has a
particularly unfavorable prognosis and in about 70% of cases occurs in the advanced stage …
particularly unfavorable prognosis and in about 70% of cases occurs in the advanced stage …
[HTML][HTML] Challenges in the treatment of small cell lung cancer in the era of immunotherapy and molecular classification
E Caliman, S Fancelli, G Petroni, MRG Michelet… - Lung Cancer, 2023 - Elsevier
For many years the standard of care for small cell lung cancer (SCLC) has remained
unchanged. Despite decades of active research, current treatment options are limited and …
unchanged. Despite decades of active research, current treatment options are limited and …
[HTML][HTML] Durvalumab with chemoradiotherapy for limited-stage small-cell lung cancer
Background The current standard treatment for limited-stage small-cell lung cancer (LS-
SCLC) is chemotherapy with concurrent chemoradiotherapy (CCRT). Methods In this single …
SCLC) is chemotherapy with concurrent chemoradiotherapy (CCRT). Methods In this single …
Global research landscape and trends of lung cancer immunotherapy: a bibliometric analysis
Y Liu, X Cheng, X Han, X Cheng, S Jiang… - Frontiers in …, 2022 - frontiersin.org
Background Immunotherapy for lung cancer has been a hot research area for years. This
bibliometric analysis aims to present the research trends on lung cancer immunotherapy …
bibliometric analysis aims to present the research trends on lung cancer immunotherapy …
SEOM-GECP Clinical guidelines for diagnosis, treatment and follow-up of small-cell lung cancer (SCLC)(2022)
R García-Campelo, I Sullivan, E Arriola, A Insa… - Clinical and …, 2023 - Springer
Small-cell lung cancer (SCLC) is a highly aggressive malignancy comprising approximately
15% of lung cancers. Only one-third of patients are diagnosed at limited-stage (LS). Surgical …
15% of lung cancers. Only one-third of patients are diagnosed at limited-stage (LS). Surgical …