Many human diseases, including metabolic, immune and central nervous system disorders,
as well as cancer, are the consequence of an alteration in lipid metabolic enzymes and their …

Cholesterol is a fundamental molecule necessary for the maintenance of cell structure and is
vital to various normal biological functions. It is a key factor in lifestyle-related diseases …

Resistance of cancer cells to chemotherapy is the first cause of cancer-associated death.
Thus, new strategies to deal with the evasion of drug response and to improve clinical …

Background Tamoxifen treatment of estrogen receptor (ER)-positive breast cancer reduces
mortality by 31%. However, over half of advanced ER-positive breast cancers are …

Background Previous studies have revealed the key functions of N6-methyladenosine (m6A)
modification in breast cancer (BC). MALAT1 as a highly m6A modified lncRNA associated …

Cholesterol, an essential molecule for cell structure, function, and viability, plays crucial
roles in the development, progression, and survival of cancer cells. Earlier studies have …

Cyclodextrins are cyclic oligosaccharides obtained by enzymatic digestion of starch. The α-,
β-and γ-cyclodextrins contain respectively 6, 7 and 8 glucopyranose units, with primary and …

Significance: Cholesterol is a type of lipid that plays a crucial role in building and
maintaining cell membranes, producing certain hormones, and aiding in digestion. The two …

Cyclodextrins (CDs) are cyclic oligosaccharides of natural origin that were discovered more
than 100 years ago. The peculiar cone-like conformation of the sugar ring, expressing a …

Aim Pancreatic cancer (PC) is one of the most aggressive tumors with dismal survival and a
high death rate due to chemotherapeutic failure. P-glycoprotein (P-gp) plays a pivotal role in …