Drug delivery scaffolds are smart alternatives to conventional formulations and allow for
controlled spatiotemporal releases of active compounds. In several fields of human health …

In situ forming implants are exposed to an extracellular matrix resembling a gel rather than
aqueous solution upon subcutaneous administration. The aim of study was to develop a gel …

Ultra-long-acting delivery platforms for HIV pre-exposure prophylaxis (PrEP) may increase
adherence and maximize public health benefit. We report on an injectable, biodegradable …

In-situ forming implants (ISFIs) represent a simple, tunable, and biodegradable polymer-
based platform for long-acting drug delivery. However, drugs with different physicochemical …

The metastasis of breast cancer is believed to have a negative effect on its prognosis.
Benefiting from the remarkable deep-penetrating and noninvasive characteristics …

The prevalence and fatality rates with fungal biofilm-associated infections urgently need to
develop targeted therapeutic approaches to augment the action of antifungal drugs. This …

In-situ forming poly (lactic-co-glycolic acid)(PLGA) implants offer a great potential for
controlled drug delivery for a variety of applications, eg periodontitis treatment. The polymer …

In situ forming implants (ISFIs) allow for a high initial intratumoral concentration and
sustained release of the chemotherapeutic. However, clinical translation is impeded …

Local drug delivery systems, such as in situ forming implants (ISFIs), allow for sustained
elevated drug concentration directly at the tumor site. However, these systems have been …

This paper reports the use of low-frequency ultrasound to influence transport in porous
hydrogels with a transducer attached in direct contact with the hydrogel. This is a different …