Gene× environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution

MC Keller - Biological psychiatry, 2014 - Elsevier
Candidate gene× environment (G× E) interaction research tests the hypothesis that the
effects of some environmental variable (eg, childhood maltreatment) on some outcome …

Self-injury

MK Nock - Annual review of clinical psychology, 2010 - annualreviews.org
People have engaged in self-injury—defined as direct and deliberate bodily harm in the
absence of suicidal intent—for thousands of years; however, systematic research on this …

The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy

M Notaras, R Hill, M van den Buuse - Molecular psychiatry, 2015 - nature.com
Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development,
differentiation and plasticity in both the developing and adult brain. A single-nucleotide …

Childhood maltreatment, depression, and suicidal ideation: critical importance of parental and peer emotional abuse during developmental sensitive periods in males …

A Khan, HC McCormack, EA Bolger… - Frontiers in …, 2015 - frontiersin.org
Background: The adverse childhood experience (ACE) study found that risk for depression
increased as a function of number of types of childhood maltreatment, and interpret this as a …

Brain-derived neurotrophic factor: role in depression and suicide

Y Dwivedi - Neuropsychiatric disease and treatment, 2009 - Taylor & Francis
Depression and suicidal behavior have recently been shown to be associated with
disturbances in structural and synaptic plasticity. Brain-derived neurotrophic factor (BDNF) …

The relationship of psychological trauma and dissociative and posttraumatic stress disorders to nonsuicidal self-injury and suicidality: A review

JD Ford, JM Gómez - Journal of trauma & dissociation, 2015 - Taylor & Francis
We reviewed research on the relationship between (a) exposure to psychological trauma
and (b) nonsuicidal self-injury (NSSI) and suicidality (suicidal ideation [SI] and suicide …

A validation study of the Dutch Childhood Trauma Questionnaire-Short Form: factor structure, reliability, and known-groups validity

BD Thombs, DP Bernstein, J Lobbestael, A Arntz - Child abuse & neglect, 2009 - Elsevier
The Childhood Trauma Questionnaire-Short Form (CTQ-SF) is a 28-item retrospective self-
report questionnaire designed to assess five dimensions of childhood maltreatment:(1) …

Brain-derived neurotrophic factor signaling and subgenual anterior cingulate cortex dysfunction in major depressive disorder

A Tripp, H Oh, JP Guilloux… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective The subgenual anterior cingulate cortex is implicated in the pathology and
treatment response of major depressive disorder. Low levels of brain-derived neurotrophic …

Neuropathology of suicide: recent findings and future directions

PE Lutz, N Mechawar, G Turecki - Molecular psychiatry, 2017 - nature.com
Suicide is a major public health concern and a leading cause of death in most societies.
Suicidal behaviour is complex and heterogeneous, likely resulting from several causes. It …

Emotional intelligence is a protective factor for suicidal behavior

CB Cha, MK Nock - Journal of the American Academy of Child & …, 2009 - Elsevier
OBJECTIVE: Little is known about what factors protect against the occurrence of suicidal
ideation and attempts. We tested whether emotional intelligence (EI)—the ability to perceive …