Old World Vipers—a review about snake venom proteomics of Viperinae and their variations
Fine-tuned by millions of years of evolution, snake venoms have frightened but also
fascinated humanity and nowadays they constitute potential resources for drug …
fascinated humanity and nowadays they constitute potential resources for drug …
Spider venom: components, modes of action, and novel strategies in transcriptomic and proteomic analyses
N Langenegger, W Nentwig, L Kuhn-Nentwig - Toxins, 2019 - mdpi.com
This review gives an overview on the development of research on spider venoms with a
focus on structure and function of venom components and techniques of analysis. Major …
focus on structure and function of venom components and techniques of analysis. Major …
Snake venomics: fundamentals, recent updates, and a look to the next decade
CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …
Investigating toxin diversity and abundance in snake venom proteomes
T Tasoulis, TL Pukala, GK Isbister - Frontiers in Pharmacology, 2022 - frontiersin.org
Understanding snake venom proteomes is becoming increasingly important to understand
snake venom biology, evolution and especially clinical effects of venoms and approaches to …
snake venom biology, evolution and especially clinical effects of venoms and approaches to …
[HTML][HTML] Analytical strategies in venomics
Snakebite envenoming is a major issue in certain developing parts of the world, with tens of
thousands of deaths and a multitude of lingering permanent medical conditions on a yearly …
thousands of deaths and a multitude of lingering permanent medical conditions on a yearly …
Modern venomics—Current insights, novel methods, and future perspectives in biological and applied animal venom research
BM von Reumont, G Anderluh, A Antunes… - …, 2022 - academic.oup.com
Venoms have evolved> 100 times in all major animal groups, and their components, known
as toxins, have been fine-tuned over millions of years into highly effective biochemical …
as toxins, have been fine-tuned over millions of years into highly effective biochemical …
Therapeutic potential of peptides derived from animal venoms: current views and emerging drugs for diabetes
A Coulter-Parkhill, S McClean… - Clinical Medicine …, 2021 - journals.sagepub.com
The therapeutic potential of venom-derived drugs is evident today. Currently, several
significant drugs are FDA approved for human use that descend directly from animal venom …
significant drugs are FDA approved for human use that descend directly from animal venom …
[HTML][HTML] Characterisation of the forest cobra (Naja melanoleuca) venom using a multifaceted mass spectrometric-based approach
CR Wang, AC Harlington, MF Snel… - Biochimica et Biophysica …, 2024 - Elsevier
Snake venoms consist of highly biologically active proteins and peptides that are
responsible for the lethal physiological effects of snakebite envenomation. In order to guide …
responsible for the lethal physiological effects of snakebite envenomation. In order to guide …
Mass spectrometry-based phosphoproteomics in clinical applications
Protein phosphorylation is an essential post-translational modification that regulates many
aspects of cellular physiology, and dysregulation of pivotal phosphorylation events is often …
aspects of cellular physiology, and dysregulation of pivotal phosphorylation events is often …
[HTML][HTML] Exploring snake venoms beyond the primary sequence: From proteoforms to protein-protein interactions
CR Wang, LO McFarlane, TL Pukala - Toxicon, 2024 - Elsevier
Snakebite envenomation has been a long-standing global issue that is difficult to treat,
largely owing to the flawed nature of current immunoglobulin-based antivenom therapy and …
largely owing to the flawed nature of current immunoglobulin-based antivenom therapy and …