[HTML][HTML] Identification of RNA binding proteins associated with dengue virus RNA in infected cells reveals temporally distinct host factor requirements
OV Viktorovskaya, TM Greco, IM Cristea… - PLoS neglected …, 2016 - journals.plos.org
Background There are currently no vaccines or antivirals available for dengue virus
infection, which can cause dengue hemorrhagic fever and death. A better understanding of …
infection, which can cause dengue hemorrhagic fever and death. A better understanding of …
[HTML][HTML] Utility of bioluminescent homogeneous nucleotide detection assays in measuring activities of nucleotide-sugar dependent glycosyltransferases and studying …
L Engel, J Alves, J Hennek, SA Goueli, H Zegzouti - Molecules, 2021 - mdpi.com
Traditional glycosyltransferase (GT) activity assays are not easily configured for rapid
detection nor for high throughput screening because they rely on radioactive product …
detection nor for high throughput screening because they rely on radioactive product …
Presentation overrides specificity: probing the plasticity of alphaviral proteolytic activity through mutational analysis
ABSTRACT Semliki Forest virus (genus Alphavirus) is an important model for studying
regulated nonstructural (ns) polyprotein processing. In this study, we evaluated the strictness …
regulated nonstructural (ns) polyprotein processing. In this study, we evaluated the strictness …
The interdomain interface in bifunctional enzyme protein 3/4A (NS3/4A) regulates protease and helicase activities
Abstract Hepatitis C (HCV) protein 3/4A (NS3/4A) is a bifunctional enzyme comprising two
separate domains with protease and helicase activities, which are essential for viral …
separate domains with protease and helicase activities, which are essential for viral …
[HTML][HTML] HCV induces telomerase reverse transcriptase, increases its catalytic activity, and promotes caspase degradation in infected human hepatocytes
Introduction Telomerase repairs the telomeric ends of chromosomes and is active in nearly
all malignant cells. Hepatitis C virus (HCV) is known to be oncogenic and potential …
all malignant cells. Hepatitis C virus (HCV) is known to be oncogenic and potential …
[HTML][HTML] pH-dependent conformational changes in the HCV NS3 protein modulate its ATPase and helicase activities
GT Ventura, ECB Costa, AM Capaccia… - PloS one, 2014 - journals.plos.org
The hepatitis C virus (HCV) infects 170 to 200 million people worldwide and is, therefore, a
major health problem. The lack of efficient treatments that specifically target the viral proteins …
major health problem. The lack of efficient treatments that specifically target the viral proteins …
[PDF][PDF] ANDREI NIKONOV
A NIK - Citeseer
Essentially every living organism studied thus far may serve as a host for the infection and
propagation of species-specific RNA viruses. An infectious virus particle, ie a virion, carries …
propagation of species-specific RNA viruses. An infectious virus particle, ie a virion, carries …