Neuropathic pain is a debilitating consequence of spinal cord injury (SCI) that remains
difficult to treat because underlying mechanisms are not yet fully understood. In part, this is …

Neuropathic pain is a common problem following spinal cord injury (SCI). Effective
analgesic therapy has been hampered by the lack of knowledge about the mechanisms …

Neurological disorders represent major health concerns in terms of comorbidity and
mortality worldwide. Despite a tremendous increase in our understanding of the …

The role of microglia and their contribution to the development and maintenance of pain
states has emerged as an attractive field of study. Sensitization of central nociceptors and …

Neuropathic pain after spinal cord injury (SCI) is common, often intractable, and can be
severely debilitating. A number of mechanisms have been proposed for this pain, which are …

Chronic neuropathic pain is often a severe and inadequately treated consequence of spinal
cord injury (SCI). Recent findings suggest that SCI pain is promoted by spontaneous activity …

Background: Altered Cl− homeostasis and GABAergic function are associated with
nociceptive input hypersensitivity. This study investigated the role of two major intracellular …

Background: Spinal cord injuries incite varying degrees of symptoms in patients, ranging
from weakness and incoordination to paralysis. Common amongst spinal cord injury (SCI) …

Matrix metalloproteinases (MMPs) constitute a family of zinc‐dependent endopeptidases
that mediate extracellular matrix turnover and associated processes, such as cell survival …

Neuropathic pain (NP) is a significant and disabling clinical problem with very few
therapeutic treatment options available. A major priority is to identify the molecular …