Evidence implicating Eph receptor tyrosine kinases and their ephrin ligands (that together
make up the 'Eph system') in cancer development and progression has been accumulating …

Single‐cell transcriptomics provides us with completely new insights into the molecular
diversity of different cell types and the different states they can adopt. The technique …

Abstract BRAF‐V600E mutation (mt) is a strong negative prognostic and predictive
biomarker in metastatic colorectal cancer (mCRC). Non‐V600Emt, designated atypical …

Eph receptors constitute the largest family of receptor tyrosine kinases, which are activated
by ephrin ligands that either are anchored to the membrane or contain a transmembrane …

The ability to 'see'genetic information directly in single cells can provide invaluable insights
into complex biological systems. In this review, we discuss recent advances of in situ …

Erythropoietin-producing hepatoma (Eph) receptor tyrosine kinases regulate the migration
and adhesion of cells that are required for many developmental processes and adult tissue …

The EPH/ephrin system constitutes a bidirectional signaling pathway comprised of a family
of tyrosine kinase receptors in tandem with their plasma membrane-bound ligand (ephrins) …

In this study, microarray data analysis, real‐time quantitative PCR and
immunohistochemistry were used to detect the expression levels of SSRP1 in colorectal …

Complex cell-to-cell communication underlies the basic processes essential for homeostasis
in the given tissue architecture. Obtaining quantitative gene-expression of cells in their …

Methods A systematic literature review was performed to identify all relevant data. The
examined databases were Scopus, Web of Science, Cochrane, Google Scholar, and …