Many behavioral and psychological symptoms of dementia (BPSD) share similarities in
executive functioning and communication deficits with those described in several …

Histamine is a critical mediator of IgE/mast cell-mediated anaphylaxis, a neurotransmitter
and a regulator of gastric acid secretion. Histamine is a monoamine synthesized from the …

Tic disorders (TD) are a group neuropsychiatric disorders with childhood onset
characterized by tics, ie repetitive, sudden, and involuntary movements or vocalizations; and …

The histaminergic system (HS) has a critical role in cognition, sleep and other behaviors.
Although not well studied in autism spectrum disorder (ASD), the HS is implicated in many …

Autistic spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
impairment in social communication and restricted/repetitive behavior patterns or interests …

Abstract Introduction: Gilles de la Tourette syndrome (GTS) is a childhood onset disorder
characterised by the presence of motor and vocal tics. The guidelines of both the American …

Since the discovery of the histamine H 3 receptor in 1983, tremendous advances in the
pharmacological aspects of H 3 receptor antagonists/inverse agonists have been …

Neurodevelopmental disorders (NDDs) are highly prevalent and severely debilitating brain
illnesses caused by aberrant brain growth and development. Resulting in cognitive, social …

Mast cells are the major effectors in allergic reactions through degranulation and release of
inflammatory, vasoactive and nociceptive mediators associated with the pathogenesis of a …

Negative symptoms in schizophrenia strongly contribute to poor functional outcomes,
however its pathogenesis is still unclear. Here, we found that histamine H1 receptor (H1R) …