Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies
JA Batsis, DT Villareal - Nature Reviews Endocrinology, 2018 - nature.com
The prevalence of obesity in combination with sarcopenia (the age-related loss of muscle
mass and strength or physical function) is increasing in adults aged 65 years and older. A …
mass and strength or physical function) is increasing in adults aged 65 years and older. A …
[HTML][HTML] The relationship between circulating testosterone and inflammatory cytokines in men
Testosterone is the predominant gonadal androgen in men. Low testosterone levels are
found to be associated with an increased in metabolic risk and systematic inflammation …
found to be associated with an increased in metabolic risk and systematic inflammation …
The anti-inflammatory effects of testosterone
VE Bianchi - Journal of the endocrine society, 2019 - academic.oup.com
Low plasma testosterone (T) levels correlated with metabolic syndrome, cardiovascular
diseases, and increased mortality risk. T exerts a significant effect on the regulation of …
diseases, and increased mortality risk. T exerts a significant effect on the regulation of …
Why does COVID‐19 kill more elderly men than women? Is there a role for testosterone?
V Papadopoulos, L Li, M Samplaski - Andrology, 2021 - Wiley Online Library
Background Recent epidemiological data indicate that there may be a gender predisposition
to COVID‐19, with men predisposed to being most severely affected, and older men …
to COVID‐19, with men predisposed to being most severely affected, and older men …
Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double …
SY Kalinchenko, YA Tishova… - Clinical …, 2010 - Wiley Online Library
Objective Men with the metabolic syndrome (MetS) have low plasma testosterone (T) levels.
The aim of this study was to establish whether the normalization of plasma T improves the …
The aim of this study was to establish whether the normalization of plasma T improves the …
[HTML][HTML] Testosterone: a vascular hormone in health and disease
DM Kelly, TH Jones - Journal of Endocrinology, 2013 - joe.bioscientifica.com
Coronary heart disease is a leading cause of premature death in men. Epidemiological
studies have shown a high prevalence of low serum testosterone levels in men with …
studies have shown a high prevalence of low serum testosterone levels in men with …
Testosterone deficiency, insulin resistance and the metabolic syndrome
M Zitzmann - Nature Reviews Endocrinology, 2009 - nature.com
Changing lifestyles and an excess of food supply in developed countries have resulted in an
increasing prevalence of overweight and obesity. As a consequence, a disorder of complex …
increasing prevalence of overweight and obesity. As a consequence, a disorder of complex …
[HTML][HTML] Do androgens modulate the pathophysiological pathways of inflammation? Appraising the contemporary evidence
The role of testosterone in the pathophysiology of inflammation is of critical clinical
importance; however, no universal mechanism (s) has been advanced to explain the …
importance; however, no universal mechanism (s) has been advanced to explain the …
[HTML][HTML] Influence of androgens on immunity to self and foreign: effects on immunity and cancer
I Ben-Batalla, ME Vargas-Delgado… - Frontiers in …, 2020 - frontiersin.org
It is well-known that sex hormones can directly and indirectly influence immune cell function.
Different studies support a suppressive role of androgens on different components of the …
Different studies support a suppressive role of androgens on different components of the …
Testosterone deficiency: a risk factor for cardiovascular disease?
TH Jones - Trends in Endocrinology & Metabolism, 2010 - cell.com
Male gender is a major risk factor for premature cardiovascular death, a relationship not yet
explained. Low testosterone in men is a risk factor for the metabolic syndrome and type 2 …
explained. Low testosterone in men is a risk factor for the metabolic syndrome and type 2 …