Membranous nephropathy (MN), the most common cause of idiopathic nephrotic syndrome
in white adults, is characterized by an accumulation of immune deposits on the outer aspect …

Systemic lupus erythematosus is characterized by a breakdown of self‐tolerance and
production of autoantibodies. Kidney involvement (ie, lupus nephritis) is both common and …

A soluble form of Alzheimer disease amyloid beta-protein (sA beta) is transported in the
blood and cerebrospinal fluid mainly complexed with apolipoprotein J (apoJ). Using a well …

Humans are genetically unable to synthesize the common mammalian sialic acid N-
glycolylneuraminic acid (Neu5Gc). However, Neu5Gc can be metabolically incorporated …

A 37-year-old man was transferred to Brigham and Women's Hospital for evaluation of
progressive renal failure. His medical history was notable for intravenous drug use and …

Antiendothelial cell antibodies (AECA) are a heterogeneous family of antibodies reacting
with endothelial cell antigens. These antibodies are found in various diseases and …

In patients with glomerulonephritis widespread crescents are associated with a poor
prognosis. Crescent formation appears to depend on the migration of mononuclear cells into …

Using an ELISA, anti-endothelial cell antibodies (AECA) have been found in sera obtained
at the time of renal biopsy in 46 out of 57 patients (81%) with systemic lupus erythematosus …

There is mounting evidence to suggest that vascular endothelial cell injury plays an
important role in the pathogenesis of preeclampsia. In this study an enzyme-linked …

The fibronectin receptor (FNR) is a transmembrane heterodimeric glycoprotein which shares
a common beta 1-chain with several other members of the integrin family of adhesion …