Endotypes and phenotypes in obstructive sleep apnea
A Malhotra, O Mesarwi, JL Pepin… - Current opinion in …, 2020 - journals.lww.com
OSA is a heterogeneous disease with highly varying underlying mechanisms. OSA has
variable clinical manifestations with definable subsets having risk of particular …
variable clinical manifestations with definable subsets having risk of particular …
More than the sum of the respiratory events: personalized medicine approaches for obstructive sleep apnea
Traditionally, the presence and severity of obstructive sleep apnea (OSA) have been defined
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …
by the apnea–hypopnea index (AHI). Continuous positive airway pressure is generally first …
Acetazolamide for OSA and central sleep apnea: a comprehensive systematic review and meta-analysis
Background Therapy options for OSA and central sleep apnea (CSA) are limited, thus many
patients remain untreated. Clinically, acetazolamide is sometimes used for CSA; however …
patients remain untreated. Clinically, acetazolamide is sometimes used for CSA; however …
Novel avenues to approach non-CPAP therapy and implement comprehensive obstructive sleep apnoea care
JL Pépin, P Eastwood, DJ Eckert - European Respiratory …, 2022 - Eur Respiratory Soc
Recent advances in obstructive sleep apnoea (OSA) pathophysiology and translational
research have opened new lines of investigation for OSA treatment and management. Key …
research have opened new lines of investigation for OSA treatment and management. Key …
Daily exposure to mild intermittent hypoxia reduces blood pressure in male patients with obstructive sleep apnea and hypertension
Rationale: Daily exposure to mild intermittent hypoxia (MIH) may elicit beneficial
cardiovascular outcomes. Objectives: To determine the effect of 15 days of MIH and in-home …
cardiovascular outcomes. Objectives: To determine the effect of 15 days of MIH and in-home …
Neural circuitry underlying waking up to hypercapnia
Obstructive sleep apnea is a sleep and breathing disorder, in which, patients suffer from
cycles of atonia of airway dilator muscles during sleep, resulting in airway collapse, followed …
cycles of atonia of airway dilator muscles during sleep, resulting in airway collapse, followed …
Prevalence, characteristics, and respiratory arousal threshold of positional obstructive sleep apnea in China: a large scale study from Shanghai Sleep Health Study …
W Huang, X Wang, C Xu, H Xu, H Zhu, S Liu, J Zou… - Respiratory …, 2022 - Springer
Purpose To evaluate the prevalence, characteristics, and respiratory arousal threshold
(ArTH) of Chinese patients with positional obstructive sleep apnea (POSA) according to the …
(ArTH) of Chinese patients with positional obstructive sleep apnea (POSA) according to the …
Sleep medicine: Practice, challenges and new frontiers
Sleep medicine is an ambitious cross-disciplinary challenge, requiring the mutual
integration between complementary specialists in order to build a solid framework. Although …
integration between complementary specialists in order to build a solid framework. Although …
Low arousal threshold: a common pathophysiological trait in patients with obstructive sleep apnea syndrome and asthma
Introduction Obstructive sleep apnea syndrome (OSAS) and asthma are two diseases with a
high epidemiological impact that may often coexist. Both diseases have underlying …
high epidemiological impact that may often coexist. Both diseases have underlying …
Physiological traits and adherence to sleep apnea therapy in individuals with coronary artery disease
AV Zinchuk, J Chu, J Liang, Y Celik… - American Journal of …, 2021 - atsjournals.org
Rationale: Untreated obstructive sleep apnea (OSA) is associated with adverse outcomes in
patients with coronary artery disease (CAD). Continuous positive airway pressure (CPAP) is …
patients with coronary artery disease (CAD). Continuous positive airway pressure (CPAP) is …