The discovery of the genetic code and tRNAs as decoders of the code transformed life
science. However, after establishing the role of tRNAs in protein synthesis, the field moved …

Aminoacyl-tRNA synthetases (ARSs) are essential enzymes for protein synthesis with
evolutionarily conserved enzymatic mechanisms. Despite their similarity across organisms …

HipA of Escherichia coli is a eukaryote-like serine-threonine kinase that inhibits cell growth
and induces persistence (multidrug tolerance). Previously, it was proposed that HipA inhibits …

Nontranslational functions of vertebrate aminoacyl tRNA synthetases (aaRSs), which
catalyze the production of aminoacyl-tRNAs for protein synthesis, have recently been …

Anti-synthetase syndrome (ASSD) is an autoimmune disease characterized by the presence
of autoantibodies targeting one of several aminoacyl t-RNA synthetases (aaRSs) along with …

Pathological mutations in tRNA genes and tRNA processing enzymes are numerous and
result in very complicated clinical phenotypes. Mitochondrial tRNA (mt-tRNA) genes are …

Aminoacyl-tRNA synthetases (AARSs) are the enzymes that catalyze the aminoacylation
reaction by covalently linking an amino acid to its cognate tRNA in the first step of protein …

Aminoacyl-tRNA synthetases (ARSs) play a vital role in protein synthesis by linking amino
acids to their cognate transfer RNAs (tRNAs). This typical function has been well recognized …

Background Dental caries is a chronic, multifactorial and biofilm-mediated oral bacterial
infection affecting almost every age group and every geographical region. Streptococcus …

Mitochondrial RNA metabolism is suggested to occur in identified compartmentalized foci, ie
mitochondrial RNA granules (MRGs). Mitochondrial aminoacyl-tRNA synthetases (mito …