Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Many bacteria, both environmental and pathogenic, exhibit the property of autoaggregation.
In autoaggregation (sometimes also called autoagglutination or flocculation), bacteria of the …

After the first ancient studies on microbial slime (the name by which the biofilm matrix was
initially indicated), multitudes of studies on the morphology, composition and physiology of …

The significance of extracellular DNA (eDNA) in biofilms was overlooked until researchers
added DNAse to a Pseudomonas aeruginosa biofilm and watched the biofilm disappear …

Bacteria secrete proteins for different purposes such as communication, virulence functions,
adhesion to surfaces, nutrient acquisition, or growth inhibition of competing bacteria. For …

Highlights•eDNA is a key component of the biofilm matrix of most bacteria.•DNase inhibits
biofilm formation and disperses young biofilms.•DNase treatment can sensitize biofilms to …

Despite considerable advances in the understanding of the pathogenesis of meningococcal
disease, this infection remains a major cause of morbidity and mortality globally. The role of …

The death and lysis of microbial cells leads to the release of cytoplasmic contents, many of
which are rapidly degraded by enzymes. However, some macromolecules survive intact and …

Bacterial colonization of biotic or abiotic surfaces results from two quite distinct physiological
processes, namely bacterial adhesion and biofilm formation. Broadly speaking, a biofilm is …

The two membranes of Gram-negative bacteria contain protein machines that have a
general function in their assembly. To interact with the extra-cellular milieu, Gram-negatives …