Epistasis can markedly affect evolutionary trajectories. In recent decades, protein-level
fitness landscapes have revealed extensive idiosyncratic epistasis among specific …

The evolutionary transition from single-celled to multicellular growth is a classic and
intriguing problem in biology. Saccharomyces cerevisiae is a useful model to study …

Division of labour between different specialized cell types is a central part of how we
describe complexity in multicellular organisms. However, it is increasingly being recognized …

How cells adjust nutrient transport across their membranes is incompletely understood.
Previously, we have shown that S. cerevisiae broadly re-configures the nutrient transporters …

Considering global economic and environmental–benefits, green renewable biofuels such
as ethanol and butanol are considered as sustainable alternatives to fossil fuels. Thus …

Bacteria play a crucial role in almost all fields of biotechnology. Among them, industrial and
medical biotechnology are the fields that are highly dependent on bacteria and their …

To persist in variable environments, populations of microorganisms have to survive periods
of starvation and be able to restart cell division in nutrient-rich conditions. Typically …

Quiescence, the temporary and reversible arrest of cell growth, is a fundamental biological
process. However, the lack of standardization in terms of reporting the experimental details …

Most cells spend the majority of their life in the non‐proliferating, quiescent state. Transition
to this state is crucial for microorganisms to survive long starvation periods and restart …

When starving, diploid Saccharomyces cerevisiae yeasts can enter into at least two stable
non-dividing states–sporulation or quiescence–and thus survive unfavorable conditions for …