Are mast cells MASTers in cancer?

G Varricchi, MR Galdiero, S Loffredo… - Frontiers in …, 2017 - frontiersin.org
Prolonged low-grade inflammation or smoldering inflammation is a hallmark of cancer. Mast
cells form a heterogeneous population of immune cells with differences in their ultra …

Mast cells, angiogenesis and lymphangiogenesis in human gastric cancer

G Sammarco, G Varricchi, V Ferraro… - International journal of …, 2019 - mdpi.com
Gastric cancer is diagnosed in nearly one million new patients each year and it remains the
second leading cause of cancer-related deaths worldwide. Although gastric cancer …

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

S Sangaletti, C Tripodo, C Chiodoni… - Blood, The Journal …, 2012 - ashpublications.org
Antineutrophil cytoplasmic antibodies (ANCAs) target proteins normally retained within
neutrophils, indicating that cell death is involved in the autoimmunity process. Still, ANCA …

Human mast cells and basophils—How are they similar how are they different?

G Varricchi, U Raap, F Rivellese… - Immunological …, 2018 - Wiley Online Library
Mast cells and basophils are key contributors to allergies and other inflammatory diseases
since they are the most prominent source of histamine as well as numerous additional …

Physiological roles of mast cells: collegium internationale allergologicum update 2019

G Varricchi, FW Rossi, MR Galdiero… - … Archives of Allergy and …, 2019 - karger.com
Mast cells are immune cells which have a widespread distribution in nearly all tissues.
These cells and their mediators are canonically viewed as primary effector cells in allergic …

Bidirectional mast cell–eosinophil interactions in inflammatory disorders and cancer

MR Galdiero, G Varricchi, M Seaf, G Marone… - Frontiers in …, 2017 - frontiersin.org
Human mast cells (MCs) and eosinophils were first described and named by Paul Ehrlich.
These cells have distinct myeloid progenitors and differ morphologically, ultrastructurally …

miR-135b mediates NPM-ALK–driven oncogenicity and renders IL-17–producing immunophenotype to anaplastic large cell lymphoma

H Matsuyama, HI Suzuki, H Nishimori… - Blood, The Journal …, 2011 - ashpublications.org
Many transformed lymphoma cells show immune-phenotypes resembling the corresponding
normal lymphocytes; thus, they provide a guide for proper diagnosis and present promising …

IL-17A is increased in the serum and in spinal cord CD8 and mast cells of ALS patients

M Fiala, M Chattopadhay, A La Cava, E Tse… - Journal of …, 2010 - Springer
The contribution of inflammation to neurodegenerative diseases is increasingly recognized,
but the role of inflammation in sporadic amyotrophic lateral sclerosis (sALS) is not well …

Mast cells: A double-edged sword in cancer

A Derakhshani, F Vahidian, M Alihasanzadeh… - Immunology letters, 2019 - Elsevier
Mast cells (MCs), a type of innate immune cells, are derived from myeloid stem cells,
sometimes known as mastocytes or labrocytes, and contain many granules rich in histamine …

[HTML][HTML] Relationship between Th17 immune response and cancer

HS Marques, BB de Brito, FAF da Silva… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Cancer is the second leading cause of death worldwide and epidemiological projections
predict growing cancer mortality rates in the next decades. Cancer has a close relationship …