Type 2 diabetes mellitus: a review of multi-target drugs

A Artasensi, A Pedretti, G Vistoli, L Fumagalli - Molecules, 2020 - mdpi.com
Diabetes Mellitus (DM) is a multi-factorial chronic health condition that affects a large part of
population and according to the World Health Organization (WHO) the number of adults …

Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: A review

P Giovannini, MJR Howes, SE Edwards - Journal of ethnopharmacology, 2016 - Elsevier
Ethnopharmacological relevance Globally 387 million people currently have diabetes and it
is projected that this condition will be the 7th leading cause of death worldwide by 2030. As …

In vitro and in vivo α-amylase and α-glucosidase inhibiting activities of the protein extracts from two varieties of bitter gourd (Momordica charantia L.)

S Poovitha, M Parani - BMC complementary and alternative medicine, 2016 - Springer
Background α-amylase and α-glucosidase digest the carbohydrates and increase the
postprandial glucose level in diabetic patients. Inhibiting the activity of these two enzymes …

Bitter melon: a panacea for inflammation and cancer

PR Dandawate, D Subramaniam, SB Padhye… - Chinese journal of …, 2016 - Elsevier
Nature is a rich source of medicinal plants and their products that are useful for treatment of
various diseases and disorders. Momordica charantia, commonly known as bitter melon or …

The Effect of Momordica charantia in the Treatment of Diabetes Mellitus: A Review

Z Liu, J Gong, W Huang, F Lu… - … and Alternative Medicine, 2021 - Wiley Online Library
In recent years, many studies of Momordica charantia (MC) in the treatment of diabetes
mellitus (DM) and its complications have been reported. This article reviewed the effect and …

Ganoderol B: a potent α-glucosidase inhibitor isolated from the fruiting body of Ganoderma lucidum

S Fatmawati, K Shimizu, R Kondo - Phytomedicine, 2011 - Elsevier
α-Glucosidase inhibitor has considerable potential as a diabetes mellitus type 2 drug
because it prevents the digestion of carbohydrates. The search for the constituents reducing …

Progress in the discovery of naturally occurring anti-diabetic drugs and in the identification of their molecular targets

JH He, LX Chen, H Li - Fitoterapia, 2019 - Elsevier
Diabetes mellitus (DM), a chronic metabolic disease, severely affects patients' life and
intensively increases risks of developing other diseases. It is estimated that 0.4 billion …

Promise of bitter melon (Momordica charantia) bioactives in cancer prevention and therapy

K Raina, D Kumar, R Agarwal - Seminars in cancer biology, 2016 - Elsevier
Recently, there is a paradigm shift that the whole food-derived components are not 'idle
bystanders' but actively participate in modulating aberrant metabolic and signaling pathways …

Momordica charantia L.—Diabetes-Related Bioactivities, Quality Control, and Safety Considerations

SS Çiçek - Frontiers in pharmacology, 2022 - frontiersin.org
Momordica charantia L.(Cucurbitaceae), commonly known as bitter gourd or bitter melon, is
widely cultivated in many tropical and subtropical regions of the world, where its unripe fruits …

Antidiabetic Potentials of Momordica charantia: Multiple Mechanisms Behind the Effects

P Chaturvedi - Journal of medicinal food, 2012 - liebertpub.com
Momordica charantia fruits are used as a vegetable in many countries. From time
immemorial, it has also been used for management of diabetes in the Ayurvedic and …