Perspectives on improving blood pressure control to reduce the clinical and economic burden of hypertension

G Mancia, FP Cappuccio, M Burnier… - Journal of Internal …, 2023 - Wiley Online Library
The clinical and economic burden of hypertension is high and continues to increase
globally. Uncontrolled hypertension has severe but avoidable long‐term consequences …

Oxidative stress, GTPCH1, and endothelial nitric oxide synthase uncoupling in hypertension

Y Wu, Y Ding, T Ramprasath, MH Zou - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Hypertension has major health consequences, which is associated with
endothelial dysfunction. Endothelial nitric oxide synthase (eNOS)-produced nitric oxide (NO) …

Worsening hypertension awareness, treatment, and control rates in Canadian women between 2007 and 2017

AA Leung, JVA Williams, FA McAlister… - Canadian Journal of …, 2020 - Elsevier
Background Hypertension continues to be the leading cause of preventable death and
disability. The objective of this study was to examine hypertension prevalence, awareness …

Outcomes of a specialized clinic on rates of investigation and treatment of primary aldosteronism

Y Liu, J King, GA Kline, RS Padwal, JL Pasieka… - JAMA …, 2021 - jamanetwork.com
Importance Primary aldosteronism (PA) is one of the most common causes of secondary
hypertension but remains largely unrecognized and untreated. Objective To understand the …

Impact of oats in the prevention/management of hypertension

J Bouchard, AF Valookaran, BM Aloud, P Raj… - Food Chemistry, 2022 - Elsevier
Oats are a rich source of a soluble fibre, beta-glucan, phenolic compounds, as well as
functional lipid and protein components that could potentially aid in preventing and …

The outcomes of endodontically treated teeth restored with custom-made cast post-and-core restorations: a retrospective cohort study

AB Suleiman, S Desai, A Tepperman… - Journal of …, 2024 - Elsevier
Introduction Custom-made cast post-and-core (CMCPC) restorations have long been used
to restore structurally deficient endodontically treated teeth (ETT). However, the evidence …

Development and validation of a hypertension risk prediction model and construction of a risk score in a Canadian population

MZI Chowdhury, AA Leung, KC Sikdar, M O'Beirne… - Scientific Reports, 2022 - nature.com
Identifying high-risk individuals for targeted intervention may prevent or delay hypertension
onset. We developed a hypertension risk prediction model and subsequent risk sore among …

Sex-Specific Associations of Aldosterone and Renin with Body Composition: A Population-Based Cohort Study

GL Hundemer, M Agharazii, F Madore… - The Journal of …, 2024 - academic.oup.com
Context Renin–angiotensin–aldosterone system (RAAS) activation is closely linked to
obesity; however, the sex-specific associations between RAAS activity and body …

[HTML][HTML] Epidemiology of resistant hypertension in Canada

AA Leung, JVA Williams, KC Tran… - Canadian Journal of …, 2022 - Elsevier
Background Resistant hypertension is associated with cardiovascular morbidity and
mortality. The objective of this study was to estimate the prevalence of apparent treatment …

Therapeutic potential of select dietary compounds in the management of hypertension and its cardiovascular complications

AF Valookaran, J Bouchard, BM Aloud, SJ Thandapilly… - Molecules, 2022 - mdpi.com
Hypertension is a common risk factor for cardiovascular disease and mortality worldwide.
Proper nutrition and diet are known to play an indispensable role in the treatment and …