Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

G Li, E De Clercq - Nature reviews Drug discovery, 2020 - nature.com
Therapeutic options for the 2019 novel coronavirus (2019-nCoV) Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children

P Zimmermann, N Curtis - The Pediatric infectious disease journal, 2020 - journals.lww.com
Coronaviruses (CoVs) are a large family of enveloped, single-stranded, zoonotic RNA
viruses. Four CoVs commonly circulate among humans: HCoV2-229E,-HKU1,-NL63 and …

COVID-19: drug targets and potential treatments

C Gil, T Ginex, I Maestro, V Nozal… - Journal of medicinal …, 2020 - ACS Publications
Currently, humans are immersed in a pandemic caused by the emerging severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), which threatens public health …

Emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2: biology and therapeutic options

S Khan, R Siddique, MA Shereen, A Ali… - Journal of clinical …, 2020 - Am Soc Microbiol
The new decade of the 21st century (2020) started with the emergence of a novel
coronavirus known as SARS-CoV-2 that caused an epidemic of coronavirus disease …

Recent discovery and development of inhibitors targeting coronaviruses

T Pillaiyar, S Meenakshisundaram, M Manickam - Drug discovery today, 2020 - Elsevier
Human coronaviruses (CoVs) are enveloped viruses with a positive-sense single-stranded
RNA genome. Currently, six human CoVs have been reported including human coronavirus …

Coronaviruses—drug discovery and therapeutic options

A Zumla, JFW Chan, EI Azhar, DSC Hui… - Nature reviews Drug …, 2016 - nature.com
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …

130 years of plant lectin research

M Tsaneva, EJM Van Damme - Glycoconjugate journal, 2020 - Springer
Lectins are proteins with diverse molecular structures that share the ability to recognize and
bind specifically and reversibly to carbohydrate structures without changing the …

Potential applications of plant biotechnology against SARS-CoV-2

T Capell, RM Twyman, V Armario-Najera, JKC Ma… - Trends in plant …, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus
responsible for an ongoing human pandemic (COVID-19). There is a massive international …

Structure-function and application of plant lectins in disease biology and immunity

A Mishra, A Behura, S Mawatwal, A Kumar… - Food and Chemical …, 2019 - Elsevier
Lectins are proteins with a high degree of stereospecificity to recognize various sugar
structures and form reversible linkages upon interaction with glyco-conjugate complexes …