Aging-related cellular and molecular processes including low-grade inflammation are major
players in the pathogenesis of cardiovascular disease (CVD) and Alzheimer's disease (AD) …

Alzheimer's disease (AD) is the most common cause of dementia worldwide and is
characterised pathologically by the accumulation of amyloid beta and tau protein …

BACKGROUND: We evaluated the amounts of amyloid beta (Aβ)) peptides in the central
nervous system (CNS) and in reservoirs outside the CNS and their potential impact on Aβ …

Abstract Alzheimer's disease (AD), is a neurodegenerative disorder that escalates with time,
exerting a significant impact on physical and mental health and leading to death. The …

Nicotinamide, the amide form of vitamin B3 (niacin), is changed to its mononucleotide
compound with the enzyme nicotinic acide/nicotinamide adenylyl-transferase, and …

Alzheimer's disease (AD) is characterized by neurotoxic amyloid-ß plaque formation in brain
parenchyma and cerebral blood vessels known as cerebral amyloid angiopathy (CAA) …

A key pathological factor of Alzheimer's disease (AD), the most prevalent form of age-related
dementia in the world, is excessive β-amyloid protein (Aβ) in extracellular aggregation in the …

Context A high ratio of plasma amyloid-β peptide 40 (Aβ 40) to Aβ 42, determined by both
high Aβ 40 and low Aβ 42 levels, increases the risk of Alzheimer disease. In a previous …

Amyloid-β peptide (Aβ) is a central player in the pathogenesis and diagnosis of Alzheimer
disease. It aggregates to form the core of Alzheimer disease-associated plaques found in …

Neurodegenerative diseases are a group of nervous system conditions characterised
pathologically by the abnormal deposition of protein throughout the brain and spinal cord …