Mas and its related G protein–coupled receptors, Mrgprs

M Bader, N Alenina, MA Andrade-Navarro… - Pharmacological …, 2014 - ASPET
The Mas-related G protein–coupled receptors (Mrgprs or Mas-related genes) comprise a
subfamily of receptors named after the first discovered member, Mas. For most Mrgprs …

Comparative assessment of the effects of DREADDs and endogenously expressed GPCRs in hippocampal astrocytes on synaptic activity and memory

SH Lee, A Mak, MHG Verheijen - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) have proven
themselves as one of the key in vivo techniques of modern neuroscience, allowing for …

Astrocytic Gq-GPCR-linked IP3R-dependent Ca2+ signaling does not mediate neurovascular coupling in mouse visual cortex in vivo

DE Bonder, KD McCarthy - Journal of Neuroscience, 2014 - Soc Neuroscience
Local blood flow is modulated in response to changing patterns of neuronal activity, a
process termed neurovascular coupling. It has been proposed that the central cellular …

Astrocyte-Selective Volume Increase in Elevated Extracellular Potassium Conditions Is Mediated by the Na+/K+ ATPase and Occurs Independently of Aquaporin 4

E Walch, TR Murphy, N Cuvelier, M Aldoghmi… - ASN …, 2020 - journals.sagepub.com
Astrocytes and neurons have been shown to swell across a variety of different conditions,
including increases in extracellular potassium concentration (^[K+] o). The mechanisms …

Recent molecular approaches to understanding astrocyte function in vivo

D Davila, K Thibault, TA Fiacco… - Frontiers in cellular …, 2013 - frontiersin.org
Astrocytes are a predominant glial cell type in the nervous systems, and are becoming
recognized as important mediators of normal brain function as well as neurodevelopmental …

Monitoring astrocytic proteome dynamics by cell type-specific protein labeling

A Müller, A Stellmacher, CE Freitag, P Landgraf… - PLoS …, 2015 - journals.plos.org
The ability of the nervous system to undergo long-term plasticity is based on changes in
cellular and synaptic proteomes. While many studies have explored dynamic alterations in …

A common role for astrocytes in rhythmic behaviours?

MJ Broadhead, GB Miles - Progress in Neurobiology, 2021 - Elsevier
Astrocytes are a functionally diverse form of glial cell involved in various aspects of nervous
system infrastructure, from the metabolic and structural support of neurons to direct …

Diversity of Evoked Astrocyte Ca2+ Dynamics Quantified through Experimental Measurements and Mathematical Modeling

M Taheri, G Handy, A Borisyuk… - Frontiers in Systems …, 2017 - frontiersin.org
Astrocytes are a major cell type in the mammalian brain. They are not electrically excitable,
but generate prominent Ca2+ signals related to a wide variety of critical functions. The …

Astrocyte and neuronal plasticity in the somatosensory system

RE Sims, JB Butcher, HR Parri, S Glazewski - Neural plasticity, 2015 - Wiley Online Library
Changing the whisker complement on a rodent's snout can lead to two forms of experience‐
dependent plasticity (EDP) in the neurons of the barrel cortex, where whiskers are …

Astrocyte calcium microdomains are inhibited by Bafilomycin A1 and cannot be replicated by low-level Schaffer collateral stimulation in situ

MY Sun, P Devaraju, AX Xie, I Holman, E Samones… - Cell Calcium, 2014 - Elsevier
Abstract Astrocyte Gq GPCR and IP 3 receptor-dependent Ca 2+ elevations occur
spontaneously in situ and in vivo. These events vary considerably in size, often remaining …