Self-reported race/ethnicity in the age of genomic research: its potential impact on understanding health disparities
TB Mersha, T Abebe - Human genomics, 2015 - Springer
This review explores the limitations of self-reported race, ethnicity, and genetic ancestry in
biomedical research. Various terminologies are used to classify human differences in …
biomedical research. Various terminologies are used to classify human differences in …
Lessons learned from GWAS of asthma
Asthma is a common complex disease of the airways. Genome-wide association studies
(GWASs) of asthma have identified many risk alleles and loci that have been replicated in …
(GWASs) of asthma have identified many risk alleles and loci that have been replicated in …
Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma
LJ Martin, J Gupta, SSSK Jyothula, M Butsch Kovacic… - PloS one, 2012 - journals.plos.org
Rationale and Objective Autophagy is a cellular process directed at eliminating or recycling
cellular proteins. Recently, the autophagy pathway has been implicated in immune …
cellular proteins. Recently, the autophagy pathway has been implicated in immune …
US childhood asthma incidence rate patterns from the ECHO consortium to identify high-risk groups for primary prevention
CC Johnson, A Chandran, S Havstad, X Li… - JAMA …, 2021 - jamanetwork.com
Importance Asthma is the leading chronic illness in US children, but most descriptive
epidemiological data are focused on prevalence. Objective To evaluate childhood asthma …
epidemiological data are focused on prevalence. Objective To evaluate childhood asthma …
The genetic etiology of eosinophilic esophagitis
LC Kottyan, S Parameswaran, MT Weirauch… - Journal of Allergy and …, 2020 - Elsevier
Eosinophilic esophagitis (EoE) is a chronic allergic disease associated with marked
mucosal eosinophil accumulation. Multiple studies have reported a strong familial …
mucosal eosinophil accumulation. Multiple studies have reported a strong familial …
Gene–vitamin D interactions on food sensitization: a prospective birth cohort study
To cite this article: Liu X, Wang G, Hong X, Wang D, Tsai H‐J, Zhang S, Arguelles L, Kumar
R, Wang H, Liu R, Zhou Y, Pearson C, Ortiz K, Schleimer R, Holt P, Pongracic J, Price HE …
R, Wang H, Liu R, Zhou Y, Pearson C, Ortiz K, Schleimer R, Holt P, Pongracic J, Price HE …
Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci
LJ Martin, H He, MH Collins, JP Abonia… - Journal of Allergy and …, 2018 - Elsevier
Background Eosinophilic esophagitis (EoE) is an esophageal inflammatory disease
associated with atopic diseases. Thymic stromal lymphopoietin (TSLP) and calpain 14 …
associated with atopic diseases. Thymic stromal lymphopoietin (TSLP) and calpain 14 …
Resolving the etiology of atopic disorders by using genetic analysis of racial ancestry
J Gupta, E Johansson, JA Bernstein… - Journal of Allergy and …, 2016 - Elsevier
Atopic dermatitis (AD), food allergy, allergic rhinitis, and asthma are common atopic
disorders of complex etiology. The frequently observed atopic march from early AD to …
disorders of complex etiology. The frequently observed atopic march from early AD to …
25‐hydroxyvitamin D3 status is associated with developing adaptive and innate immune responses in the first 6 months of life
AP Jones, N D'Vaz, S Meldrum… - Clinical & …, 2015 - Wiley Online Library
Summary Background Vitamin D (25 [OH] D3) status in early life has been linked to the risk
of allergic disease in multiple observational studies. While immunomodulating properties …
of allergic disease in multiple observational studies. While immunomodulating properties …
Individualized risk for statin-induced myopathy: current knowledge, emerging challenges and potential solutions
QP Feng, RA Wilke, TM Baye - Pharmacogenomics, 2012 - Taylor & Francis
Skeletal muscle toxicity is the primary adverse effect of statins. In this review, we summarize
current knowledge regarding the genetic and nongenetic determinants of risk for statin …
current knowledge regarding the genetic and nongenetic determinants of risk for statin …