Background Chronic kidney disease (CKD) is becoming a major public health problem
worldwide. This article reviews the published evidence of prevalence of CKD in population …

OBJECTIVE:: To summarize recent knowledge on the small molecular weight protein
cystatin C (cys-C) and its use as a marker of the glomerular filtration rate (GFR). METHODS …

The International Conference on Harmonization considers older people a 'special
population', as they differ from younger adults in terms of comorbidity, polypharmacy …

As for the whole human body, the kidney undergoes age-related changes which translate in
an inexorable and progressive decline in renal function. Renal aging is a multifactorial …

OBJECTIVES:: To perform a systematic review comparing the diagnostic accuracy of CysC
with SCr. METHODS:: MEDLINE and EMBASE (January 1984–February 2006) were …

There is a growing population of older adults requiring admission to the intensive care unit
(ICU). This population outpaces the ability of clinicians with geriatric training to assist in their …

Methods We evaluated sex as the variable of interest in a health care–based study of adults
(n= 227,847) with at least one outpatient eGFR< 60 ml/min per 1.73 m 2 measurement …

Despite the high prevalence of chronic kidney disease among the elderly, few studies have
described their loss of kidney function. We sought to determine the progression of kidney …

Objective To develop practical recommendations for the use of low-molecular-weight
heparins (LMWHs) as prophylaxis and treatment of venous thromboembolism and acute …

The elderly consume a disproportionate amount of prescription and nonprescription
medications. Alterations in physiology, polypharmacy, multiple prescribers, and other factors …