2021 EULAR recommendations regarding lifestyle behaviours and work participation to prevent progression of rheumatic and musculoskeletal diseases

JM Gwinnutt, M Wieczorek, A Balanescu… - Annals of the …, 2023 - ard.bmj.com
Objectives A European League Against Rheumatism taskforce was convened to review the
literature and develop recommendations on lifestyle behaviours for rheumatic and …

Epicardial adipose tissue may mediate deleterious effects of obesity and inflammation on the myocardium

M Packer - Journal of the American College of Cardiology, 2018 - jacc.org
Epicardial adipose tissue has unique properties that distinguish it from other depots of
visceral fat. Rather than having distinct boundaries, the epicardium shares an unobstructed …

White adipocyte dysfunction and obesity-associated pathologies in humans

CE Hagberg, KL Spalding - Nature Reviews Molecular Cell Biology, 2024 - nature.com
The prevalence of obesity and associated chronic diseases continues to increase
worldwide, negatively impacting on societies and economies. Whereas the association …

Adipocyte and lipid metabolism in cancer drug resistance

Y Cao - The Journal of clinical investigation, 2019 - Am Soc Clin Investig
Development of novel and effective therapeutics for treating various cancers is probably the
most congested and challenging enterprise of pharmaceutical companies. Diverse drugs …

Effects of physical exercise and body weight on disease-specific outcomes of people with rheumatic and musculoskeletal diseases (RMDs): systematic reviews and …

JM Gwinnutt, M Wieczorek, G Cavalli, A Balanescu… - RMD open, 2022 - rmdopen.bmj.com
Background A European League Against Rheumatism (EULAR) taskforce was convened to
develop recommendations for lifestyle behaviours in rheumatic and musculoskeletal …

Smoking, alcohol consumption and disease-specific outcomes in rheumatic and musculoskeletal diseases (RMDs): systematic reviews informing the 2021 EULAR …

M Wieczorek, JM Gwinnutt, M Ransay-Colle… - RMD open, 2022 - rmdopen.bmj.com
Background A EULAR taskforce was convened to develop recommendations for lifestyle
behaviours in rheumatic and musculoskeletal diseases (RMDs). The aim of this paper was …

Characterization of the inflammatory‐metabolic phenotype of heart failure with a preserved ejection fraction: a hypothesis to explain influence of sex on the evolution …

M Packer, CSP Lam, LH Lund… - European Journal of …, 2020 - Wiley Online Library
Accumulating evidence points to the existence of an inflammatory‐metabolic phenotype of
heart failure with a preserved ejection fraction (HFpEF), which is characterized by …

'Difficult to treat'rheumatoid arthritis: current position and considerations for next steps

Y Tan, MH Buch - RMD open, 2022 - rmdopen.bmj.com
The European Alliance of Associations for Rheumatology recently defined difficult to treat
(D2T) rheumatoid arthritis (RA) and provided points to consider in its management. This …

Effect of body mass index on treatment response of biologic/targeted-synthetic DMARDs in patients with rheumatoid arthritis, psoriatic arthritis or axial spondyloarthritis …

CG Gialouri, M Pappa, G Evangelatos… - Autoimmunity …, 2023 - Elsevier
Background Overweight and/or obese patients with inflammatory arthritis (IA) have higher
disease activity and lower chances of achieving and/or maintaining the treatment targets …

Multi‑faceted role of cancer‑associated adipocytes in the tumor microenvironment

H Yao, S He - Molecular Medicine Reports, 2021 - spandidos-publications.com
Adipocytes are a type of stromal cell found in numerous different tissues that serve an active
role in the tumor microenvironment. Cancer‑associated adipocytes (CAAs) display a …