Senescence, brain inflammation, and oligomeric tau drive cognitive decline in Alzheimer's disease: Evidence from clinical and preclinical studies
Aging, tau pathology, and chronic inflammation in the brain play crucial roles in synaptic
loss, neurodegeneration, and cognitive decline in tauopathies, including Alzheimer's …
loss, neurodegeneration, and cognitive decline in tauopathies, including Alzheimer's …
Innate neuroimmunity across aging and neurodegeneration: a perspective from amyloidogenic evolvability
G Ho, L Lam, T Tran, J Wei… - Frontiers in Cell and …, 2024 - pmc.ncbi.nlm.nih.gov
In Alzheimer's Disease (AD), amyloidogenic proteins (APs), such as β-amyloid (Aβ) and tau,
may act as alarmins/damage-associated molecular patterns (DAMPs) to stimulate …
may act as alarmins/damage-associated molecular patterns (DAMPs) to stimulate …
[HTML][HTML] Mesenchymal Stem Cells from Familial Alzheimer's Patients Express MicroRNA Differently
LJ Rochín-Hernández, LS Rochín-Hernández… - International Journal of …, 2024 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the predominant
form of dementia globally. No reliable diagnostic, predictive techniques, or curative …
form of dementia globally. No reliable diagnostic, predictive techniques, or curative …
Innate neuroimmunity across aging and neurodegeneration: a perspective from amyloidogenic evolvability
G Ho, L Lam, T Tran, J Wei… - Frontiers in Cell and …, 2024 - frontiersin.org
In Alzheimer's Disease (AD), amyloidogenic proteins (APs), such as β-amyloid (Aβ) and tau,
may act as alarmins/damage-associated molecular patterns (DAMPs) to stimulate …
may act as alarmins/damage-associated molecular patterns (DAMPs) to stimulate …
The role of high mobility group proteins in cellular senescence mechanisms
J Chen, H Li, Y Huang, Q Tang - Frontiers in Aging, 2024 - frontiersin.org
Aging is a universal physiological phenomenon, and chronic age-related diseases have
become one of the leading causes of human mortality, accounting for nearly half of all …
become one of the leading causes of human mortality, accounting for nearly half of all …
Novel Method for Collecting Hippocampal Interstitial Fluid Extracellular Vesicles (EVISF) in a Mouse Model of Alzheimer's Disease
MC Pait - 2023 - search.proquest.com
Methods In vivo microdialysis was used to collect hippocampal ISF from 3-and 9-month-old,
unanaesthetized, unrestrained, APPswe/PS1ΔE9 (APP/PS1), a mouse model of Aβ …
unanaesthetized, unrestrained, APPswe/PS1ΔE9 (APP/PS1), a mouse model of Aβ …