Coagulation and fibrinolysis in diabetes

SH Alzahrani, RA Ajjan - Diabetes and Vascular Disease …, 2010 - journals.sagepub.com
Atherothrombotic complications are the main cause of mortality in subjects with diabetes.
Premature atherosclerosis, increased platelet reactivity and activation of coagulation factors …

Coagulation and atherothrombotic disease

R Ajjan, PJ Grant - Atherosclerosis, 2006 - Elsevier
Atherothrombotic disease arises secondary to a complex gene–environment interaction. In
the initial stages, the condition is clinically silent but with more advanced disease, an …

Atorvastatin for lowering lipids

SP Adams, M Tsang, JM Wright - Cochrane Database of …, 2015 - cochranelibrary.com
Background This represents the first update of this review, which was published in 2012.
Atorvastatin is one of the most widely prescribed drugs and the most widely prescribed statin …

Lipoprotein (a): current perspectives

I Gouni-Berthold, HK Berthold - Current vascular …, 2011 - ingentaconnect.com
Recent data from genetic and epidemiological studies strongly support a causal relationship
between elevated lipoprotein (a)[Lp (a)] concentrations and the development of …

Influence of statin use on endothelial function: from bench to clinics

J Martinez-Gonzalez, L Badimon - Current pharmaceutical …, 2007 - ingentaconnect.com
Endothelial dysfunction has been shown to be a prognostic factor for cardiovascular disease
and improvement of endothelial dysfunction prevents cardiovascular event presentation …

Lipoprotein (a): medical treatment options for an elusive molecule

K G. Parhofer - Current pharmaceutical design, 2011 - benthamdirect.com
Elevated levels of lipoprotein (a) are causally related to premature atherosclerosis. It is
therefore of interested to evaluate by which treatment modalities elevated lipoprotein (a) …

Endothelial function, arterial stiffness and lipid lowering drugs

K Tziomalos, VG Athyros, A Karagiannis… - Expert opinion on …, 2007 - Taylor & Francis
The endothelium is a dynamic organ that plays a pivotal role in cardiovascular homeostasis.
Alteration in endothelial function precedes the development of atherosclerosis and …

Biomarkers for atherosclerosis: pathophysiological role and pharmacological modulation

N Ferri, R Paoletti, A Corsini - Current opinion in lipidology, 2006 - journals.lww.com
Altered levels of soluble biomarkers are associated with cardiovascular disease, and
profiling of multiple biomarkers for atherosclerosis will be a useful indicator for better risk …

Cardiovascular disease and heritability of the prothrombotic state

RA Ajjan, RAS Ariëns - Blood reviews, 2009 - Elsevier
Atherothrombotic disease remains a major cause of mortality worldwide, and family
clustering suggests an important contribution of genetic factors to disease pathogenesis …

High-dose atorvastatin in peripheral arterial disease (PAD): Effect on endothelial function, intima-media-thickness and local progression of PAD

S Spring, R Simon, B van der Loo… - Thrombosis and …, 2008 - thieme-connect.com
Beneficial effects of aggressive lipid-lowering with high-dose atorvastatin (80 mg/day) have
been demonstrated in patients with coronary and cerebrovascular disease. The impact of …