Calcium signaling and cell proliferation

MCX Pinto, AH Kihara, VAM Goulart, FMP Tonelli… - Cellular signalling, 2015 - Elsevier
Cell proliferation is orchestrated through diverse proteins related to calcium (Ca 2+)
signaling inside the cell. Cellular Ca 2+ influx that occurs first by various mechanisms at the …

Anti-cancer agents in proliferation and cell death: the calcium connection

E Varghese, SM Samuel, Z Sadiq, P Kubatka… - International journal of …, 2019 - mdpi.com
Calcium (Ca2+) signaling and the modulation of intracellular calcium ([Ca2+] i) levels play
critical roles in several key processes that regulate cellular survival, growth, differentiation …

[HTML][HTML] Plasma membrane calcium channels in cancer: Alterations and consequences for cell proliferation and migration

N Déliot, B Constantin - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
The study of calcium channels in molecular mechanisms of cancer transformation is still a
novel area of research. Several studies, mostly conducted on cancer cell lines, however …

Resveratrol activates autophagic cell death in prostate cancer cells via downregulation of STIM1 and the mTOR pathway

S Selvaraj, Y Sun, P Sukumaran… - Molecular …, 2016 - Wiley Online Library
Resveratrol (RSV), a natural polyphenol, has been suggested to induce cell cycle arrest and
activate apoptosis‐mediated cell death in several cancer cells, including prostate cancer …

Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease

YS Prakash - American Journal of Physiology-Lung Cellular …, 2016 - journals.physiology.org
Airway structure and function are key aspects of normal lung development, growth, and
aging, as well as of lung responses to the environment and the pathophysiology of important …

Calcium promotes human gastric cancer via a novel coupling of calcium-sensing receptor and TRPV4 channel

R Xie, J Xu, Y Xiao, J Wu, H Wan, B Tang, J Liu, Y Fan… - Cancer research, 2017 - AACR
Although dietary calcium intake has long been recommended for disease prevention, the
influence of calcium in development of cancer in the upper gastrointestinal tract has not …

Calcium homeostasis, transporters, and blockers in health and diseases of the cardiovascular system

G Bkaily, D Jacques - International Journal of Molecular Sciences, 2023 - mdpi.com
Calcium is a highly positively charged ionic species. It regulates all cell types' functions and
is an important second messenger that controls and triggers several mechanisms, including …

Sol-gel synthesis of lithium doped mesoporous bioactive glass nanoparticles and tricalcium silicate for restorative dentistry: Comparative investigation of physico …

HO Simila, AR Boccaccini - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Introduction: The sol-gel method for production of mesoporous bioactive glass nanoparticles
(MBGNs) has been adapted to synthesize tricalcium silicate (TCS) particles which, when …

TRP channels in cardiac and intestinal fibrosis

R Inoue, LH Kurahara, K Hiraishi - Seminars in Cell & Developmental …, 2019 - Elsevier
It is now widely accepted that advanced fibrosis underlies many chronic inflammatory
disorders and is the main cause of morbidity and mortality of the modern world. The …

Short-and long-term (trophic) purinergic signalling

G Burnstock - … Transactions of the Royal Society B …, 2016 - royalsocietypublishing.org
There is long-term (trophic) purinergic signalling involving cell proliferation, differentiation,
motility and death in the development and regeneration of most systems of the body, in …