Aerosol delivery devices for obstructive lung diseases

RA Pleasants, DR Hess - Respiratory Care, 2018 - rc.rcjournal.com
Drug delivery by inhalation is the principal strategy to treat obstructive lung diseases, which
affect about 15% of the population in the United States. Aerosol delivery devices have …

Nebulized therapies in COPD: past, present, and the future

IZ Barjaktarevic, AP Milstone - International journal of chronic …, 2020 - Taylor & Francis
Current guidelines recommend inhalation therapy as the preferred route of drug
administration for treating patients with chronic obstructive pulmonary disease (COPD) …

[HTML][HTML] Development of remdesivir as a dry powder for inhalation by thin film freezing

S Sahakijpijarn, C Moon, JJ Koleng, DJ Christensen… - Pharmaceutics, 2020 - mdpi.com
Pharmaceutics | Free Full-Text | Development of Remdesivir as a Dry Powder for Inhalation
by Thin Film Freezing Next Article in Journal Continuous-Flow Production of Liposomes …

[图书][B] Fundamentals and applications of controlled release drug delivery

J Siepmann, RA Siegel, MJ Rathbone - 2012 - Springer
This book approaches the subject from a mechanistic perspective that pitches the language
at a level that is understandable to those entering the field and who are not familiar with its …

Andrographis paniculata Dosage Forms and Advances in Nanoparticulate Delivery Systems: An Overview

S Raman, V Murugaiyah, T Parumasivam - Molecules, 2022 - mdpi.com
Andrographis paniculata is a well-known Asian medicinal plant with a major
phytoconstituent of diterpene lactones, such as andrographolide, 14-deoxyandrographolide …

Formulation and evaluation of inhaled Sildenafil-loaded PLGA microparticles for treatment of pulmonary arterial hypertension (PAH): A novel high drug loaded …

M Almutairi, A Hefnawy, A Almotairy, A Alobaida… - International Journal of …, 2024 - Elsevier
In recent years, several techniques were employed to develop a local sustained pulmonary
delivery of sildenafil citrate (SC) as an alternative for the intravenous and oral treatment of …

Formulation and optimization of sildenafil citrate-loaded PLGA large porous microparticles using spray freeze-drying technique: a factorial design and in-vivo …

H Shahin, BP Vinjamuri, AA Mahmoud… - International Journal of …, 2021 - Elsevier
The oral administration of sildenafil citrate (SC) for the treatment of pulmonary arterial
hypertension is associated with several drawbacks. The study aimed to design and …

[HTML][HTML] Aerosol delivery via invasive ventilation: a narrative review

HL Lin, JB Fink, H Ge - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
In comparison with spontaneously breathing non-intubated subjects, intubated,
mechanically ventilated patients encounter various challenges, barriers, and opportunities in …

Optimising aerosolized therapies in critically ill patients

J Dhanani, LU Taniguchi, OT Ranzani - Intensive Care Medicine, 2022 - Springer
Amongst the machines that help save lives in the intensive care unit (ICU) environment,
aerosol drug delivery devices play a special role. Aerosolization can rapidly achieve high …

Mask use with spacers/valved holding chambers and metered dose inhalers among children with asthma

A Volerman, U Balachandran, M Siros… - Annals of the …, 2021 - atsjournals.org
Inhaler misuse is highly prevalent and associated with high morbidity and costs. For metered
dose inhalers, proper use can be supported with devices such as spacers/valved holding …