Pathogenesis of Proteus mirabilis Infection

CE Armbruster, HLT Mobley, MM Pearson - EcoSal Plus, 2018 - Am Soc Microbiol
Proteus mirabilis, a Gram-negative rod-shaped bacterium most noted for its swarming
motility and urease activity, frequently causes catheter-associated urinary tract infections …

FimH and anti-adhesive therapeutics: a disarming strategy against uropathogens

M Sarshar, P Behzadi, C Ambrosi, C Zagaglia… - Antibiotics, 2020 - mdpi.com
Chaperone-usher fimbrial adhesins are powerful weapons against the uropathogens that
allow the establishment of urinary tract infections (UTIs). As the antibiotic therapeutic …

Pathogenesis of Proteus mirabilis in catheter-associated urinary tract infections

F Yuan, Z Huang, T Yang, G Wang, P Li, B Yang… - Urologia …, 2021 - karger.com
Proteus mirabilis (PM) is a Gram-negative rod-shaped bacterium and widely exists in the
natural environment, and it is most noted for its swarming motility and urease activity. PM is …

The immune responses to different Uropathogens call individual interventions for bladder infection

L Li, Y Li, J Yang, X Xie, H Chen - Frontiers in Immunology, 2022 - frontiersin.org
Urinary tract infection (UTI) caused by uropathogens is the most common infectious disease
and significantly affects all aspects of the quality of life of the patients. However …

Urinary tract infection of mice to model human disease: practicalities, implications and limitations

AJ Carey, CK Tan, DS Ipe, MJ Sullivan… - Critical reviews in …, 2016 - Taylor & Francis
Urinary tract infections (UTIs) are among the most common bacterial infections in humans.
Murine models of human UTI are vital experimental tools that have helped to elucidate UTI …

Hacking the immune response to solid tumors: harnessing the anti-cancer capacities of oncolytic bacteria

JM Roe, K Seely, CJ Bussard, E Eischen Martin… - Pharmaceutics, 2023 - mdpi.com
Oncolytic bacteria are a classification of bacteria with a natural ability to specifically target
solid tumors and, in the process, stimulate a potent immune response. Currently, these …

Transurethral instillation with fusion protein MrpH.FimH induces protective innate immune responses against uropathogenic Escherichia coli and Proteus mirabilis

M Habibi, MR Asadi Karam, S Bouzari - Apmis, 2016 - Wiley Online Library
Urinary tract infections (UTI s) are among the most common infections in human. Innate
immunity recognizes pathogen‐associated molecular patterns (PAMP s) by Toll‐like …

Genomes comparison of two Proteus mirabilis clones showing varied swarming ability

D Gmiter, I Pacak, S Nawrot, G Czerwonka… - Molecular Biology …, 2023 - Springer
Background Proteus mirabilis is a Gram-negative bacteria most noted for its involvement
with catheter-associated urinary tract infections. It is also known for its multicellular migration …

Native flagellin does not protect mice against an experimental Proteus mirabilis ascending urinary tract infection and neutralizes the protective effect of MrpA fimbrial …

P Scavone, A Umpiérrez, A Rial, JA Chabalgoity… - Antonie van …, 2014 - Springer
Proteus mirabilis expresses several virulence factors including MR/P fimbriae and flagella.
Bacterial flagellin has frequently shown interesting adjuvant and protective properties in …

[HTML][HTML] Relevance of iron metabolic genes in biofilm and infection in uropathogenic Proteus mirabilis

V Iribarnegaray, MJ González, AL Caetano… - Current Research in …, 2021 - Elsevier
The microorganisms are found in the environment, forming sessile communities embedded
in an extracellular matrix of their own production, called biofilm. These communities have a …