Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …

Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …

The role of glutathione in autism spectrum disorder (ASD) is emerging as a major topic, due
to its role in the maintenance of the intracellular redox balance. Several studies have …

Despite evidence that deleterious variants in the same genes are implicated across multiple
neurodevelopmental and neuropsychiatric disorders, there has been considerable interest …

Background Autism spectrum disorder (ASD) is a neurodevelopmental condition, which is
characterized by clinical heterogeneity and high heritability. Core symptoms of ASD include …

The molecular mechanisms and evolutionary changes accompanying synapse development
are still poorly understood,. Here we generate a cross-species proteomic map of synapse …

The genetic etiology and underlying mechanism of autism spectrum disorder (ASD) remain
elusive. SHANK family genes (SHANK1/2/3) are well known ASD-related genes. However …

Background Autism spectrum disorder (ASD) is mainly characterized by deficits in social
interaction and communication and repetitive behaviors. Known causes of ASD are …

The postsynaptic density (PSD) of excitatory synapses is built from a wide variety of
scaffolding proteins, receptors, and signaling molecules that collectively orchestrate synaptic …

Environmental factors, such as medication during pregnancy, are one of the major causes of
autism spectrum disorder (ASD). Valproic acid (VPA) intake during pregnancy has been …