Since the industrial revolution, air pollution has become a major problem causing several
health problems involving the airways as well as the cardiovascular, reproductive, or …

Carbon dioxide (CO2) is a fundamental physiological gas known to profoundly influence the
behaviour and health of millions of species within the plant and animal kingdoms in …

Persistent symptoms and radiographic abnormalities suggestive of failed lung repair are
among the most common symptoms in patients with COVID-19 after hospital discharge. In …

Muscle dysfunction often occurs in patients with chronic obstructive pulmonary diseases
(COPD) and affects ventilatory and non-ventilatory skeletal muscles. We have previously …

The nuclear receptor sub-family 4 group A (NR4A) family are early response genes that
encode proteins that are activated in several tissues/cells in response to a variety of …

Asthma is a common chronic respiratory disorder with relatively good outcomes in the
majority of patients with appropriate maintenance therapy. However, in a small minority …

Carbon dioxide (CO2) has long been considered, at best, a waste by-product of metabolism,
and at worst, a toxic molecule with serious health consequences if physiological …

Carbon dioxide (CO2), a primary product of oxidative metabolism, can be sensed by
eukaryotic cells eliciting unique responses via specific signalling pathways. Severe lung …

Carbon dioxide (CO2) is produced in eukaryotic cells primarily during aerobic respiration,
resulting in higher CO2 levels in mammalian tissues than those in the atmosphere. CO2 like …

Hypercapnia occurs when the partial pressure of carbon dioxide (CO2) in the blood exceeds
45 mmHg. Hypercapnia is associated with several lung pathologies and is transcriptionally …