The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …

Under normal physiological conditions the brain primarily utilizes glucose for ATP
generation. However, in situations where glucose is sparse, eg, during prolonged fasting …

Astrocytes contribute to the complex cellular pathology of Alzheimer's disease (AD).
Neurons and astrocytes function in close collaboration through neurotransmitter recycling …

There is emerging evidence that diet has a major modulatory influence on brain-gut-
microbiome (BGM) interactions with important implications for brain health, and for several …

Astrocytes play key roles in the regulation of brain energy metabolism, which has a major
impact on brain functions, including memory, neuroprotection, resistance to oxidative stress …

Background Brain energy metabolism is impaired in Alzheimer's disease (AD), which may
be mitigated by a ketogenic diet. We conducted a randomized crossover trial to determine …

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the
accumulation of amyloid β in the form of extracellular plaques and by intracellular …

Introduction Counteracting impaired brain glucose metabolism with ketones may improve
cognition in mild cognitive impairment (MCI). Methods Cognition, plasma ketone response …

Alzheimer's disease (AD) is a progressive neurodegenerative disease in the elderly with
dementia, memory loss, and severe cognitive impairment that imposes high medical costs …

Since it was first generally accepted that the two amino acids glutamate and GABA act as
principal neurotransmitters, several landmark discoveries relating to this function have been …